OBJECTIVES The aim of the study was to assess the relationship between baseline and post-procedural Thrombolysis In Myocardial Infarction (TIMI) epicardial blood flow grade and mortality in patients with acute coronary syndromes (ACS) who were treated with early percutaneous coronary intervention (PCI). BACKGROUND The impact of baseline and post-procedural TIMI flow grade on mortality in pati...

casa (computer assisted semen analysis) systems are designed to assist andrologist labour. most available casa systems are not accurate or so expensive. therefore labours use manual methods to provide parameters. although some companies have achieved appropriate accuracy, they have not released their methods. so proposing methods in this area might be useful for groups who intend to design new ...

BACKGROUND Transthoracic Doppler echocardiography (TTDE) enables evaluation of distal left anterior descending coronary artery (LAD) flow. The purpose of this study was to test whether TTDE can differentiate coronary reperfusion with Thrombolysis in Myocardial Infarction (TIMI) grade 3 from TIMI grade < or =2 in patients with anterior acute myocardial infarction (AMI). METHODS AND RESULTS In ...

BACKGROUND A residual stenosis and/or microvascular damage have been proposed as mechanisms of TIMI 2 flow for acute myocardial infarction. Coronary flow dynamics were assessed in patients with TIMI 2 flow to predict whether additional intervention would improve TIMI grade. METHODS AND RESULTS In 35 patients who had a successfully recanalized anterior acute myocardial infarction using angiopl...

Mariani et al. add to a growing body of the literature associating elevated white blood cell counts to adverse outcomes in the setting of ST-elevation MI (STEMI). For the first time, the authors highlight the association of elevated monocytes counts particularly with late left ventricular (LV) functional recovery following primary percutaneous coronary intervention (PCI) for STEMI. A wealth of ...

OBJECTIVES We hypothesized that recognition of systolic flow reversal (pulsatile flow) after thrombolytic administration on coronary angiography is associated with angiographic and electrocardiogram findings reflecting impaired myocardial perfusion, as well as poorer clinical outcomes. BACKGROUND Reversal of systolic flow on Doppler velocity wire recordings has been associated with impaired t...

OBJECTIVE To determine the correlation of thrombolysis in myocardial infarction (TIMI) risk score with extent of coronary artery disease (CAD) in patients with acute coronary syndrome (ACS). METHODS We conducted a descriptive study among 200 consecutive patients admitted with ACS at Tabba Heart Institute, Karachi from June to December 2008. The TIMI risk score was stratified on seven standard...

BACKGROUND The no-reflow phenomenon is an uncommon and critical occurrence which myocardial reperfusion does not restore to its optimal level. Several predisposing factors of the no-reflow phenomenon have been identified. However, at present we know little about clinical predictors of no-reflow after percutaneous coronary intervention (PCI). OBJECTIVES In this study, we evaluated clinical pre...

Pre-percutaneous coronary intervention (PCI) Thrombolysis In Myocardial Infarction (TIMI) grade 3 flow has been identified as a predictor of final TIMI grade 3 flow and better survival. Yet pharmacologic strategies increasing the rates of pre-PCI TIMI grade 3 flow resulted in more bleeding, without a benefit in survival. The aim of this study was to identify the predictors and implications of s...

OBJECTIVE Slow coronary flow (SCF) is a phenomenon characterized by delayed opacification of coronary arteries in the absence of epicardial occlusive disease, in which many aetiological factors such as microvascular and endothelial dysfunction, and small vessel disease have been implicated. We aimed to investigate the epicardial resistance in relation with SCF by using fractional flow reserve (...