نتایج جستجو برای: thyroidstimulating hormone tsh
تعداد نتایج: 146883 فیلتر نتایج به سال:
Ghrelin is a peptide hormone produced mainly in the gastrointestinal tract known to regulate several physiological functions including gut motility, adipose tissue accumulation and hunger sensation leading to increased bodyweight. Studies have found a correlation between the plasma levels of thyroid hormones and ghrelin, but an effect of ghrelin on the human thyroid has never been investigated ...
The mechanism by which the thyrotropic or the thyroid-stimulating hormone (TSH) causes such marked growth and accelerated function of the thyroid remains a perplexing problem. Significant experiments in this direction have been reported by Rawson et al. (6, 8) who exposed TSH to slices of various organs in tissue culture. Of the various tissues studied, only thyroid, thymus, and lymph node were...
Hepatocyte nuclear factor-4 alpha (HNF-4α) is an orphan nuclear receptor with important roles in hepatic metabolism. Protein phosphorylation plays a functional role in its nuclear localization, DNA binding, and transactivation. Thyroid-stimulating hormone (TSH) is a hormone produced by the anterior pituitary gland, whose direct effect on the metabolic pathway has been observed. Our previous stu...
Removal of a limited number of amino acid residues at the COOH termini of the peptide chains of the glycoprotein hormone, thyrotropin (TSH) shows that the integrity of these regions is important both in subunit-subunit interactions and in uivo biological response. Treatment of the native hormone with a mixture of carboxypeptidases A and B leads to loss of half of the biological activity with th...
Resistance to thyroid hormone is an uncommon condition. We report the clinical and laboratory findings of a case with both resistance to thyroid hormone and, a reduced capacity to produce and respond to thyroid hormone. RTH is a disorder characterized by elevated circulating thyroid hormones, state of non-suppressed pituitary TSH secretion and refractoriness to hormone action in peripheral tiss...
SH is defined as a serum thyroid stimulating hormone (TSH) above the upper limit of the reference range, with a serum T4 and T3 thyroxine within the reference range. Other causes of a raised TSH such as a past history of thyroid disease and patients on T4 hormone treatment need to be excluded. Although patients with subclinical thyroid disease are usually asymptomatic, but nearly 30% have sympt...
Background Thyroid hormone is essential for neurological development, particularly in the developing brain. Iodine is the important constituent of thyroid hormone. Its requirement during pregnancy is increased. Elevated neonatal thyroid stimulating hormone (TSH) is a sensitive indicator of iodine insufficiency in pregnant women. Our previous study in the year 2000 demonstrated that median urine...
BACKGROUND Thyroid-stimulating hormone (TSH) promotes expression of thyroid hormones which are essential for metabolism, growth, and development. Second-line drugs to treat tuberculosis (TB) can cause hypothyroidism by suppressing thyroid hormone synthesis. Therefore, TSH levels are routinely measured in TB patients receiving second-line drugs, and thyroxin treatment is initiated where indicate...
Human thyroid stimulating hormone (TSH) is a glycoprotein secreted by the anterior part of the pituitary gland. TSH plays an important physiological role in the regulation of hypothalamic-pituitary-thyroid axis by modulating the release of the thyroid hormones from the thyroid gland. It induces iodine uptake by the thyroid, promotes thyroid epithelial differentiation and growth, and protects th...
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