Background: Fine-needle aspiration (FNA) is the current standard for triaging patients with thyroid nodules into operative and nonoperative therapy. In 2007, the National Cancer Institute (NCI) held a Thyroid FNA State of the Science Conference, where a 6-tiered classification system was proposed to standardize reporting of thyroid FNA results. One category, designated "follicular lesion of und...

background: the aim of this study was to understand any association between differentiated thyroid carcinoma (dtc) and ile3434thr xrcc7 gene polymorphism (genbank accession number: rs7830743). dtc is the most prevalent thyroid neoplasm, which includes papillary and follicular cell carcinoma. xrcc7 gene encodes a protein that functions in non-homologous end joining dna repair pathway. non-synony...

Oncocytoma is a neoplasm consisting of oncocytes that is found in the salivary gland, kidney, and thyroid. Adrenocortical oncocytoma is particularly uncommon, and most cases reported are benign and nonfunctioning. Here, we report a 20 cm adrenal mass associated with necrosis that was identified as an oncocytic adrenocortical tumor with uncertain malignant potential through histopathological eva...

CONTEXT Molecular markers hold the promise of improved diagnostic yield in thyroid fine-needle biopsy. The Afirma gene expression classifier (GEC), available commercially, reports a negative predictive value of 94% in the diagnosis of benign nodules after indeterminate cytology. However, there are currently no independent studies of the performance of this assay. OBJECTIVE The aim was to asse...

Of all solid cancers presenting in adults, papillary thyroid cancers generally carry best longterm prognosis. However, very little is understood about the molecular pathogenesis of this neoplasm. Any patient presenting with thyroid nodule-initial work up will be fine needle aspiration cytology (FNAC). Surgical treatment depends on FNA finding, age and clinical presentation. After surgical debul...

An unusual case of a mucin secreting benign microfollicular adenoma of the thyroid in a 30 year old euthyroid woman is reported. Histologically, the lesion was characterised by follicular cells with the appearance of signet ring cells. Histochemistry showed the mucin content of these cells to consist uniformly of sulphated acid mucins; positive thyroglobulin immunostaining was also shown. The p...

nized as being a significant subclass of thyroid neoplasm. This case report presents 3 rare cases of a primary B-cell lymphoma and we feature the various ultrasonographic (US) imaging findings. The US findings of thyroid lymphoma have previously been reported to be extremely hypoechoic masses when there is diffuse bilateral involvment, and a homogenous low echoic mass in solitary nodules (1). W...

BACKGROUND Preoperative ultrasound (US) evaluation of central and lateral neck compartments is recommended for all patients undergoing a thyroidectomy for malignant or suspicious for malignancy cytologic or molecular findings. Our aim was to find out how frequent was recurrence in regional lymph nodes in patients with follicular or Hürthle cell neoplasm and usefulness of preoperative neck US in...