نتایج جستجو برای: thymocyte globulin

تعداد نتایج: 21308  

2015
Wilson Savino Daniella Arêas Mendes-da-Cruz Daiane Cristina Ferreira Golbert Ingo Riederer Vinicius Cotta-de-Almeida

Intrathymic T-cell differentiation is a key process for the development and maintenance of cell-mediated immunity, and occurs concomitantly to highly regulated migratory events. We have proposed a multivectorial model for describing intrathymic thymocyte migration. One of the individual vectors comprises interactions mediated by laminins (LMs), a heterotrimeric protein family of the extracellul...

2012
Ana Rosa Pérez Luiz Ricardo Berbert Ailin Lepletier Silvia Revelli Oscar Bottasso Suse Dayse Silva-Barbosa Wilson Savino

Previous studies revealed a significant production of inflammatory cytokines together with severe thymic atrophy and thymocyte migratory disturbances during experimental Chagas disease. Migratory activity of thymocytes and mature T cells seem to be finely tuned by cytokines, chemokines and extracellular matrix (ECM) components. Systemic TNF-α is enhanced during infection and appears to be cruci...

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