-Bilateral kidney ligation of mice immediately before injection of misonidazole (MIS) prolongs the plasma half-life of this radiosensitizer from about 2 h (in normal mice) to 10-11 h, similar to that in man. Kidney ligation does not, however, change the relative proportions of MIS and its 0-demethylated metabolite, Ro-05-9963, for the first 12 h after MIS injection. Kidney ligation was used wit...

Experiments were conducted to examine the interrelationships between methionine, choline and inorganic sulfate in the diet of weanling pigs, and to evaluate the selenium (Se) status of pigs fed diets with or without supplemental sulfate. Two trials utilized 288 weanling (3-wk-old) pigs allotted to dietary treatment based on weight, sex and litter origin. There were six pigs/pen and three replic...

This study was conducted to determine cultivars which grown at Van ecological conditions and their some important agricultural plant properties in 2013 summer season Van. In the used 14cultivars officially registered such as Yaşa-05, Hisar, Azkan, Işık-05, Seçkin, İnci, Diyar-95, Taek, Çağatay, Hasanbey, Aksu, Çakır, Zühal, Ilgaz. The trial by using randomized complete blocks design with three ...

A laboratory silo trial, two lamb metabolism trials and a lamb growth trial were conducted to compare the nitrogen (N) value of swine methane digester effluent (MDE) to that of urea. Using laboratory silos (four/treatment), fermentation characteristics were measured for silages containing cracked corn, ground wheat straw and MDE added at levels of 0, 4, 8 or 12% of silage dry matter (DM). Lacti...

Sixteen Yorkshire gilts were assigned randomly to four semi-purified diets fed throughout gestation and lactation. Two sources of fat (stripped lard and stripped corn oil) were fed factorially with two levels of vitamin E (atocopheryl acetate, 0 and 100 IU/kg of diet). All diets were supplemented with .05 ppm Se as Na2SeO3. Reproductive performance (litter size, individual pig birth weight, wea...

Previous data suggest that the analgesic effect of morphine may be modulated by P-glycoprotein (P-gp) inhibition. The effects of the P-gp inhibitor GF120918 on brain distribution and antinociceptive effects of morphine were examined in a rat cerebral microdialysis model. Pretreatment with GF120918 increased both the area under the concentration-time curve of unbound morphine in brain extracellu...

BACKGROUND Oxidative stress plays an important role in the pathogenesis of asthma. Interestingly, a low airway pH and a high concentration of 8-isoprostane, a marker of oxidative stress, has been reported to cause inflammatory airway diseases. However, the relationship between these 2 markers and pulmonary function has not been determined in mild asthma patients. METHODS pH and 8-isoprostane ...

A 111-d finishing study evaluated animal growth and carcass characteristics using 138 steers (366 kg) in a randomized complete block design with a 2 x 3 factorial arrangement of treatments. The dietary treatments consisted of no supplemental fat or 3.5% tallow or soybean oil soapstock (SS) fed with .6% and .9% dietary Ca. Fat increased DMI (P less than .05) but interacted with Ca level (P less ...

In the abstract, these sentences (page 1, line 5) should be: 'Additionally, hepatic betaine-homocysteine methyltransferase concentration as well as its mRNA abundance and lecithin level were found increased (P < 0. 05) by betaine supplementation in both basal diet-fed rats and high-fat diet-fed rats. Betaine administration in high-fat diet-fed rats exhibited a higher (P < 0.05) concentration of...