The transmission of SARS-CoV-2, the novel severe acute respiratory syndrome corona virus have caused disease (Covid-19) worldwide pandemic. Overcoming this pandemic requires identifying patients to avoid further spread disease. Real-time, sensitive, and cost-efficient methods for detecting COVID-19 are crucial. Optical sensors provide one such means achieve this, especially using surface plasmo...

A free sulfhydryl group previously has been shown to be required for carbohydrate binding to the lectin from lima bean (Phaseolus lunatus) (Gould, N. R. and Scheinberg, S. L. (1970) Arch. Biochem. Biophys. 141, 607-613). Modification of this group by sulfhydryl reagents was specifically inhibited by D-GalNAc. We have further examined the reactivity of sulfhydryl groups in lima bean lectin with ...

Standard measurements of free thiol on cell surfaces use the uptake of thiol-reactive substances which are incapable of traversing the membrane (reviewed in [l]). One problem is that dead cells are incapable of excluding such reagents, so that there is a risk of systematically high bias in the results, especially in delicate cells from patients. For example, one group showed a 3OOO% increase in...

In this study, magnetic Fe3O4 nanoparticles were synthesized and the surfaces of modified with thiol groups. The chitosan polymer was allyl groups then bound to by thiol-en click reaction. drugs paclitaxel (PTX) doxorubicin (DOX) loaded separately together into prepared hybrid material, drug releases from material studied. aim paper is present results on controlled release DOX PPT cancer chitos...

Background: Lipid peroxide plays an important role in inflammatory lung disease. Increased epithelial permeability produced by cigarette smoke is likely to be mediated through depletion of thiol proteins. Imbalance between oxidants and thiol proteins is also an established fact in these patients. Materials & methods: In the present study 30 healthy non-smokers were served as controls and 20 pat...

Schematic overview of the thiol assisted polymersome attachment and formation solid supported planar polymer membranes.

Dendrimers up to the fourth generation were successfully prepared via the divergent growth strategy using a combination of thiol-ene "click" chemistry and traditional esterification reactions. The thiol-ene reactions were conducted under solvent-free, ambient conditions at room temperature by irradiating with UV light. The fourth-generation dendrimers were subsequently functionalized with carbo...

Thiol-ene chemistry was exploited in droplet-based microfluidics to fabricate advanced microcapsules with tunable encapsulation, degradation, and thermal properties. In addition, by utilizing the thiol-ene photopolymerization with tunable cross-link density, we demonstrate the importance of monomer conversion on the retention of omniphilic cargo in double emulsion templated microcapsules. Furth...

Glutathione and soluble thiol content were examined in a broad spectrum of bacteria. Significant soluble thiol was present in all cases. The thiol compound was glutathione in most of the gram-negative bacteria but not in most of the gram-positive bacteria studied. Glutathione was absent in four anerobes and one microaerophile but was present in a blue-green bacterium. The glutathione content of...

Objective(s): The effects of Curcuma longa (C. longa) and curcumin on total and differential WBC count and oxidant, antioxidant biomarkers, in rat model of asthma were evaluated. Materials and Methods: Total and differential WBC count in the blood, NO2, NO3, MDA, SOD, CAT and thiol levels in serum were examined in control, asthma, Asthmatic rats treated with C. longa (0.75, 1.50, and 3.00 mg/ml...