We describe the synthesis of gold nanorods (NRs) nucleated by HgTe nanoparticles (NPs) of average size 3 nm in diameter. Growth of ~200 nm by ~50 nm NRs on various surfaces is achieved by using an intermediary polyelectrolyte layer. A poly(dimethyldiallylammonium) chloride (PDDA) monolayer on the surface attracts the thioglycolic acid (TGA) capped HgTe NPs and assists in one-dimensional gold gr...

2-(6,8-Dibromo-2-methylquinazolin-4-yloxy)-acetohydrazide (4) was prepared by the reaction of 6,8-dibromo-2-methylbenzo-[d][1,3]oxazin-4-one with formamide to afford quinazolinone 2, followed by alkylation with ethyl chloroacetate to give the ester 3. Treatment of ester 3 with hydrazine hydrate and benzaldehyde afforded 4 and styryl quinazoline 5. The hydrazide was reacted with triethyl orthofo...

Introduction Keratins are strong fibrous proteins with high degree of stability, found in hair, wool and in hard tissues such as horn, hoof, and nail. Keratin biomaterials in the form of sponge, films were developed from wool and human hair for various biomedical applications such as wound dressings and neural tissue engineering application. In the present work, an effort has been made to extra...

Various 7-chloro-6-fluoro-2-arylidenylaminobenzo(1,3)thiazole (2a-h) have been synthesized by the condensation of 7-chloro-6-fluoro-2-aminobenzo(1,3)thiazole (1) with different aromatic aldehydes. The Schiff's bases on reaction with acetyl chloride, chloroacetyl chloride and phenyl acetyl chloride yielded 1-(7-chloro-6-fluorobenzothiazol-2-yl)-3,4-substituted-aryl-azetidin-2-ones (3a-x). Simila...

The synthesis and pharmacological activity of some aminoalcoholic derivatives of 8-caffeinethioglycolic acid was studied. The structure of the synthesized compounds was proved by microanalysis, IRand H-NMR spectra. All of the investigated compounds were found to be practically non-toxic (LD50 p.o. > 5 g kg in mice) and less toxic compared to caffeine. The compounds were investigated for antihyp...

BACKGROUND Thioglycolic acid (TGA) is widely used in the hairdressing industry, which mostly caters to women. Recently, TGA has been reported to impair several organs, especially reproductive ones such as testes and ovaries. The reproductive toxicity of TGA on females has become an issue that cannot be neglected. METHODOLOGY/PRINCIPAL FINDINGS In the present work, superovulated female mice we...

ZnSe-based nanocrystals (ca. 4-5 nm in diameter) emitting in blue region (ca. 445 nm) were incorporated in spherical small silica particles (20-40 nm in diameter) by a reverse micelle method. During the preparation, alkaline solution was used to deposit the hydrolyzed alkoxide on the surface of nanocrystals. It was crucially important for this solution to include Zn(2+) ions and surfactant mole...

Novel 2-arylthiazolidin-4-one derivatives (8a-q and 11) have been synthesized in good-to-excellent yields (70-96%) by one-pot three-component condensation-cyclization reaction of aromatic or aliphatic primary amines, aromatic aldehydes, and thioglycolic acid in polypropylene glycol at 110°C temperature. The in vitro antimicrobial activity of the synthesized 2-arylthiazolidin-4-ones was investig...