نتایج جستجو برای: thiazolidine 4 ones
تعداد نتایج: 1407163 فیلتر نتایج به سال:
Seasonal and pandemic influenza outbreaks remain a major human health problem. Inhibition of the endonuclease activity of influenza RNA-dependent RNA polymerase is attractive for the development of new agents for the treatment of influenza infection. Our earlier studies identified a series of 5- and 6-phenyl substituted 3-hydroxypyridin-2(1H)-ones that were effective inhibitors of influenza end...
RESEARCH ARTICLE Anticonvulsant Activities of 4-benzylidene-6-(4-methyl-phenyl)-4,5dihydropyridazin-(2H)-ones and 4-benzylidene-6-(4-chlorophenyl)-4,5-dihydropyridazin-(2H)-ones Mohammad Asif and Anita Singh Department of Pharmacy, GRD (P.G) Institute of Management and Technology, Dehradun, 2480009, India Department of Pharmaceutical Sciences, Kumaun University Campus, Bhimtal, Nainital, India
Various 7-chloro-6-fluoro-2-arylidenylaminobenzo(1,3)thiazole (2a-h) have been synthesized by the condensation of 7-chloro-6-fluoro-2-aminobenzo(1,3)thiazole (1) with different aromatic aldehydes. The Schiff's bases on reaction with acetyl chloride, chloroacetyl chloride and phenyl acetyl chloride yielded 1-(7-chloro-6-fluorobenzothiazol-2-yl)-3,4-substituted-aryl-azetidin-2-ones (3a-x). Simila...
This paper reports an experimental and a theoretical study of the structures and standard (p(o) = 0.1 MPa) molar enthalpies of formation of the synthetic reagents 1,3-thiazolidine-2-thione [CAS 96-53-7] and 1,3-oxazolidine-2-thione [CAS 5840-81-3]. The enthalpies of combustion and sublimation were measured by rotary bomb combustion calorimetry, and the Knudsen effusion technique and gas-phase e...
Thiazolidinediones (TZDs) are five-membered heterocyclic having sulfur, nitrogen, and oxygen atoms in their ring structure and exhibiting potent as well as wide range of pharmacological activities. Variety of substituents on the thiazolidine-2,4-dione nucleus or as hybrid molecules when combined with other heterocyclic rings produce wide range of biological activities suchas antihyperglycemics,...
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