Aim of the present work was to develop alginate raft forming tablets for controlled release pantoprazole sodium sesquihydrate (PSS). Box behnken design was used to optimize 15 formulations with three independent and three dependent variables. Physical tests of all formulations were within pharmacopoeial limits. Raft was characterized by their strength, thickness, resilience, acid neutralizing c...

Alginate is a family of natural polysaccharides, widely used in industry and medicine for many applications, with its non toxic nature, gentle sol/gel transition procedure and low cost, alginate inferior biomechanical properties have limited its utility especially in tissue engineering. Additionally, ionically cross-linked alginate hydrogels generally lose most of their initial mechanical and s...

Bulk crystallisation of protein therapeutic molecules towards their controlled drug delivery is of interest to the biopharmaceutical industry. The complexity of biotherapeutic molecules is likely to lead to complex material properties of crystals in the solid state and to complex transitions. This complexity is explored using batch crystallised lysozyme as a model. The effects of drying and mil...

The development of biosensors based on DNA hybridization requires a more precise knowledge of the thermodynamics of the hybridization at a solid interface. In particular, the selectivity of hybridization can be affected by a lot of parameters such as the single-strand (ss)DNA density, the pH, the ionic strength or the temperature. The melting temperature, T(m), is in part a function of the ioni...

Many authors have suggested the existence of a functional dependence between the cervical muscle and mastication muscles. In the sequence of this functional dependence postural, changes, specially in the head and neck, can influence certain neuronal-muscular patterns leading to the development temporomandibular disorders. The existing of hyperactivity of the mastication muscle in bruxism patien...

Bio-oil produced from the hydrothermal liquefaction (HTL) of biomass is unstable and cannot be transported over long distances to a refinery for upgrading transportation fuel. This study examined effect solvent on stability bio-oils derived HTL sugarcane bagasse. The accelerated aging test (0–8 days at 80 °C) was used assess these oils with aid indicators such as water content, molecular weight...

Semi-continuous production of xanthan gum using self-immobilized Xanthomonas campestris cells in biofilm reactors was studied. Fermentation carried out two different designs reactor equipped with a) stainless-steel support (SSS) and b) polyethylene (PES). performed three cycles refreshing the media at beginning each: cycle 1, 0−27 h; 2, 27−54 3, 54–78.5 h. Results showed that glucose consumptio...

Breast cancer is one of the most prevalent causes death among women across globe. Early detection best strategy for reducing mortality rate. Currently, mammography standard screening modality, which has its shortcomings. To complement this thermal infrared-based Computer-Aided Diagnosis (CADx) tools have been presented as economical, less hazardous, and a suitable solution various age groups. A...

Abstract Microcrystalline Cellulose, MCC, is widely used in pharmaceutical, cosmetics, food, and other industries. This study aims to see changes the properties that occur MCC from rice straw waste after transformation using TGJPC-120 isolated bacteria soil. The biotransformation process was carried out bacterial culture flask placed an incubator shaker for 2 days at 37 °C, a rate of 100 rpm. s...

Abstract The prediction of porosity is a crucial task for metal based additive manufacturing techniques such as laser powder bed fusion. Short wave infrared thermography an in-situ monitoring tool enables the measurement surface radiosity during exposure. Based on thermogram data, thermal history component can be reconstructed which closely related to resulting mechanical properties and formati...