The spread of antibiotic-resistant pathogens requires new treatments. Small molecule precursor compounds that produce oxidative biocides with well-established antimicrobial properties could provide a range of new therapeutic products to combat resistant infections. The aim of this study was to investigate a novel biomaterials-based approach for the manufacture, targeted delivery and controlled ...

In this paper, we report on the development of a new and broadly applicable strategy to produce thermally mendable polymeric materials, demonstrated with an epoxy/poly(-caprolactone) (PCL) phase-separated blend. The initially miscible blend composed of 15.5 wt % PCL undergoes polymerization-induced phase separation during cross-linking of the epoxy, yielding a "bricks and mortar" morphology whe...

Metal-organic frameworks (MOFs) have received attention for a myriad of potential applications including catalysis, gas storage, and gas separation. Coordinatively unsaturated metal ions often enable key functional behavior of these materials. Most commonly, MOFs have been metalated from the condensed phase (i.e., from solution). Here we introduce a new synthetic strategy capable of metallating...

Poly(lactic acid) (PLA) stands out as the most promising biodegradable alternative to conventional petrochemical-based polymers for manufacturing of high-performance materials applied in medicine, pharmacy, food, textile, and electronic industry. This review was aimed present up-to-date technologies PLA processing including melt blending molding, hot extrusion, 3D printing, foaming, impregnatio...

A novel strong electron-acceptor unit, 9,10-difluorodithieno[3,2-a:2′,3′-c]phenazine (DTPz), is synthesized and applied in the design of two donor-acceptor type emitters displaying long-lived delayed emission. Using either 9,9-dimethyl-9,10-dihydroacridine (DMAC) or triisopropyl-substituted benzo[1,2-b:4,5-b']dithiophene (BDT-TIPS) as donor component, push-pull chromophores exhibiting charge-tr...

Abstract The application range of aerogels, especially in the life-science sector, can be extended by utilizing biocompatible polymers such as polylactic acid (PLA). However, low glass transition temperature (Tg) PLA and challenging gelation techniques limit supercritical CO 2 (scCO ) drying thus PLA-aerogel production. aim this work is to overcome challenge provide a better understanding therm...

Materials Polypropylene microfiltration membranes were obtained from Membrana GmbH (Germany) and Beijing Normal University (China), respectively. One was prepared by thermally induced phase separation with mean pore size of 0.2 μm and porosity of 75%, another was prepared by biaxially orientation with mean pore size of 0.20.02 μm and porosity of 45%. Poly(vinylidene fluoride) (PVDF) microfiltr...

A silk fibroin/poly (vinyl alcohol) porous scaffold with a water vapor transmission rate of 2125 ± 464 g/m(2)/day has been developed via thermally induced phase separation (gelation) and freeze-drying process. A hierarchical architecture of micropores and nanofibers was observed inside the scaffolds, and the related structures were analyzed. The viability and proliferation of 3T3 fibroblasts we...