This review highlights rare earth biphenolates as they offer a diversity over simpler aryloxides, well their efficacy catalysts and initiators in organic transformations polymerisations.

Fibrosis, characterized by excessive extracellular matrix accumulation, is a common feature of many connective tissue diseases, notably scleroderma (systemic sclerosis). Experimental studies suggest that a complex network of intercellular interactions involving endothelial cells, epithelial cells, fibroblasts and immune cells, using an array of molecular mediators, drives the pathogenic events ...

Chloroform and other trihalomethanes are contaminants of drinking water that have been demonstrated to be carcinogenic in laboratory animals. Determination of the mechanism of carcinogenicity of chloroform is required so that the animal data can be extrapolated to estimate the human health hazard. The extent of the binding of chloroform to rat liver and kidney DNA was approximately 0.1% the lev...

For animals living in groups, one of the important questions is to understand what are the decisionmaking mechanisms that lead to choosing a motion direction or leaving an area while preserving group cohesion. Here, we analyse the initiation of collective departure in zebrafish Danio rerio. In particular, we observed groups of 2, 3, 5, 7 and 10 zebrafish swimming in a two resting sites arena an...

OBJECTIVES The objectives of this study were to quantify the proportion of US patients with newly diagnosed rheumatoid arthritis (RA) in whom disease-modifying antirheumatic drug (DMARD) therapy was initiated within 12 months following diagnosis, to determine mean time to initiation, to compare the characteristics of initiators versus noninitiators, and to identify factors associated with nonin...

BACKGROUND Use of nonsteroidal anti-inflammatory drugs (NSAID) has been associated with a decrease in breast cancer risk, but it is unknown if they also reduce mammographic density, a strong intermediate marker of breast cancer risk. METHODS We investigated NSAID use and mammographic density in 29,284 postmenopausal women who had two screening mammograms at Group Health in Seattle. We used ph...