Ameliorative potential of antioxidants –vitamins C and E on blood profile of Clarias gariepinus fed diets contaminated with varied levels of fumonisin B1 (FB1) was evaluated. Fusarium cultured maize containing FB1 were used to formulate diets containing approximately 2.5, 5.0, and 7.5 mg FB1/kg constituting diets 2, 3, and 4, respectively and other nine diets constituting Diets 5 - 13 with the ...

Oxidative stress is actively involved in Friedreich's Ataxia (FA), thus pharmacological targeting of the antioxidant machinery may have therapeutic value. Here, we analyzed the relevance of the antioxidant phase II response mediated by the transcription factor Nrf2 on frataxin-deficient cultured motor neurons and on fibroblasts of patients. The in vitro treatment of the potent Nrf2 activator su...

The gut microbiota is composed of a large number microbes, usually regarded as commensal bacteria. It has become gradually clear that gastrointestinal affects pathophysiology and the central nervous system (CNS) function by modulating signaling pathways microbiota-gut-brain (MGB) axis. This bidirectional MGB axis communication primarily acts through neuroendocrine, neuroimmune, autonomic system...

to compare the nutritional value of rapeseed meal and cottonseed meal in holstein cows, feeding 20 lactating holstein cows each with an average weight of 580± 34 kg and 100± 10 days in milk were studied in a randomized complete block design. the experimental diets consisted of 4 levels of 0, 8, 14 and 25 percent rapeseed meal replaced with cottonseed meal and barley grain in the diets. diets we...

Whether low-fat, high-carbohydrate (CHO) diets or moderately high-fat, high-monounsaturated fatty acid (MUFA) diets are preferable for the treatment and prevention of diabetes has been a matter of debate. High-fat diets based on MUFA-rich oils or whole foods have been compared with high-CHO diets for effects on several cardiovascular risk outcomes in diabetic subjects. Early studies using metab...

Awareness of the nutritional requirements of inpatients has been sadly neglected for many years. Students in British medical schools are taught little about clinical nutrition and the role of the dietitian. Dietitians, on the other hand, spend four years learning the science of nutrition and dietetics. In most hospitals in Britain dietitians are responsible for giving advice on a wide range of ...

The effects of dietary-induced acidosis on the growth and rates of complete regression of Sarcoma 180 in mice have been studied. The experiments here reported have demonstrated that mineral acidification of laboratory food produces a late decrease in tumor growth and significantly increases the rates of complete tumor regression. Blood acid-base studies also demonstrate the effects of these die...

All children with moderate wasting, or moderate or severe stunting, have in common a higher risk of dying and the need for special nutritional support. In contrast to children suffering from life-threatening severe acute malnutrition, there is no need to feed these children with highly fortified therapeutic foods designed to replace the family diet. Their dietary management should be based on i...

Malnutrition in children and adults with advanced liver disease represents a tremendous challenge as the nutritional problems are multifactorial. This Editorial comments the articles appearing in this special issue of Nutrients, "Nutrition and Liver disease" dealing with multiple diagnostic and therapeutic features that relate the outcomes of liver disease to nutrition. To improve quality of li...