background: leishmaniasis is a parasitic disease caused by different species of leishmania parasites with a wide range of clinical manifestations . antimonial compounds such as meglumine antimoniate (glucantime) are the first line drugs for the treatment of leishmaniasis. however, according to reports of the drug resistance of parasites, the efficacy of antimonial compounds is low. the atp-bind...

The aim of the present paper is to discuss in some detail the Laguerre geometry (cf. [1], [6]) which arises from the 3-dimensional real algebra L := R(ε), where ε = 0. This algebra generalizes the algebra of real dual numbers D = R(ε), where ε = 0. The Laguerre geometry over D is the geometry on the so-called Blaschke cylinder (Figure 1); the non-degenerate conics on this cylinder are called ch...

Background: Interferons are some kind of natural cytokines which express in response to a variety of antigens including viral RNA, bacterial products, and tumor proteins. Interferon beta is used in the treatment of autoimmune diseases such as multiple sclerosis. Moreover, this drug inhibits cellular proliferation as well as angiogenesis and as a result, helps to cure cancer. In this research, i...

The adaptive interactive systems are still in the beginning of their practical use. There are many scientific prototypes but only few real-life applications using adaptive technology. A lot of Internet applications use profiling techniques but they are still parameter scheduling systems, which are not really adaptive. The adaptive interactive systems have large-scaled very complex structures wi...