According to classical concepts, uric acid is presumably filtered at the renal glomeruli andl reabsorbed but not secreted by the renal tubules in man (Berliner et at., 1950). Recent work (Y#{252} and Gutman, 1959) suggests that uric acid may, however, be both secreted and reabsorbed by the tubules. In this species probenecid and salicylates may either increase renal excretion of uric acid, and ...

The hyperuricaemia associated with gout is believed to be due to overproduction of uric acid, to impaired renal excretion of uric acid, or to alterations in both mechanisms (Seegmiller, 1966). In all likelihood, gout encompasses a heterogeneity of biochemical disorders, the metabolic or enzymatic bases of which with one exception, have not yet been completely delineated. The Lesch-Nyhan syndrom...

Gutman et al. introduced the concepts of energy E (G) and Laplacian energy EL(G) for a simple graph G, and furthermore, they proposed a conjecture that for every graph G, E (G) is not more than EL(G). Unfortunately, the conjecture turns out to be incorrect since Liu et al. and Stevanović et al. constructed counterexamples. However, So et al. verified the conjecture for bipartite graphs. In the ...

It is well known that the incorporation of wetting agents in drug solutions for local application enhances the penetration of the drug into the tissues (McKee et al., 1943; Bellows and Gutman, 1943; Trim and Alexander, 1946). Ginsburg and Robson (1945) have shown that when dodecyl sodium sulphate is incorporated in solutions of sodium sulphacetamide applied to the cornea, the increase in penetr...

Search engines are among the most popular and useful services on the web. Ingwersen and Järvelin (2005) recommend evaluating an IR system based on how much it helps the user achieve their task effectively and efficiently. Therefore, to evaluate a search engine holistically, the users’ rating of the results should be taken into account. Many previous studies have evaluated the effectiveness of w...

The energy of a graph was introduced by Gutman in 1978 as the sum of the absolute values of the eigenvalues of its adjacency matrix. We study the energy of integral circulant graphs, also called gcd graphs. These are Cayley graphs on cyclic groups (i.e. there adjacency matrix is circulant) each of whose eigenvalues is an integer. Given an arbitrary prime power p, we determine all integral circu...

1031 Vertex-degree-based molecular structure descriptors of benzenoid systems and phenylenes IVAN GUTMAN* and BORIS FURTULA** Faculty of Science, University of Kragujevac, P. O. Box 60, 34000 Kragujevac, Serbia (Received 12 December 2011) Abstract. Several recently published papers report expressions for various vertex-degree-based molecular structure descriptors of benzenoid systems and phenyl...

Let $G$ be a finite group. The intersection graph of is whose vertex set the all proper non-trivial subgroups and two distinct vertices $H$ $K$ are adjacent if only $H\cap K \neq \{e\}$, where $e$ identity group $G$. In this paper, we investigate some properties exploring topological indices such as Wiener, Hyper-Wiener, first second Zagreb, Schultz, Gutman eccentric connectivity $D_{2n}$ for $...

Cocycles are a key object in Antolín Camarena and Szegedy's theory of nilspaces. We introduce variants these cocycles, named nilcycles, enabling us to give conditions which guarantee that an ergodic group extension strictly distal system admits topological model. In particular we show if the base space is dynamical nilspace then model may be chosen for extension. This approach combined with str...