Accurate delineation of clinical target volume (CTV) is critical in the effective management of squamous cell carcinoma (SCC) of esophagus using radiation therapy. Accurate delineation may improve the probability of local control and reduce the risk of complications. However, there are no consistent standards on the proper size of the margins added to the gross tumor volume (GTV). Different ins...

PURPOSE The path of subsequent dwell positions of an afterloader source being moved through a ring applicator for cervix cancer brachytherapy deviates from an ideal circle and the position of marker wires. This can lead to deviations of several millimetres between real and assumed dwell positions for treatment planning with simplified source path models. The aim of this study was to test video-...

To investigate the plan quality of tri-Co-60 intensity-modulated radiation therapy (IMRT) with magnetic-resonance image-guided radiation therapy compared with volumetric-modulated arc therapy (VMAT) for prostate cancer. Twenty patients with intermediate-risk prostate cancer, who received radical VMAT were selected. Additional tri-Co-60 IMRT plans were generated for each patient. Both primary an...

PURPOSE To evaluate dosimetric variations of planning target volume (PTV) on critical organs such as rectal wall, bladder and femoral head, when the patient size changes due to weight loss in prostate volumetric modulated arc therapy (VMAT). METHODS Three patients with small (32.0 cm3 ), medium (48.4 cm3 ) and large (86.5 cm3 ) prostate, selected from a group of 30 were planned for prostate V...

PURPOSE To evaluate tumor shrinking kinetics in order to implement image-guided brachytherapy (IGBT) for the treatment of patients with cervix cancer. MATERIAL AND METHODS This study has prospectively evaluated tumor shrinking kinetics of thirteen patients with uterine cervix cancer treated with combined chemoradiation. Four high dose rate brachytherapy fractions were delivered during the cou...

PURPOSE The purpose of this case series is to describe the treatment and outcomes of a cohort of patients with inoperable early-stage endometrioid endometrial cancer with 3D image-guided high-dose-rate (HDR) intracavitary brachytherapy. MATERIALS AND METHODS A review was performed of patients with early-stage endometrial cancer who underwent primary radiation treatment between 2010 and 2016. ...

BACKGROUND Locoregional recurrence is a major problem in esophageal cancer patients treated with definitive concomitant chemoradiotherapy. Approximately half of the patients fail locoregionally. We analyzed the impact of enlarged radiation field size and higher radiation dose incorporated to chemoradiotherapy on oncologic outcome. METHODS Seventy-four consecutive patients with histologically ...

BACKGROUND The purpose of the study was to analyse the dosimetric differences when using 10 MV instead of 6 MV for VMAT treatment plans for post-prostatectomy irradiation of the prostate bed. METHODS AND MATERIALS Ten post-prostatectomy prostate bed irradiation cases previously treated using 6 MV with volumetric modulated arc therapy (VMAT) were re-planned using 10 MV with VMAT. Prescription ...

BACKGROUND To compare intracavitary brachytherapy (ICBT) planning methods for cervical cancer, based on either orthogonal radiographs (conventional plan) or CT sections (CT plan); the comparison focused on target volume coverage and dose volume analysis of organs at risk (OARs), by representing point doses defined by the International Commission on Radiation Units and Measurement (ICRU) and dos...

OBJECTIVE To investigate the feasibility of using intensity-modulated radiotherapy (IMRT) with reduced, high-dose target volumes for nasopharyngeal carcinoma (NPC). METHODS The first 57 patients (admitted from October 2005 to May 2008) were treated with large-target-volume IMRT (LV-IMRT). For the LV-IMRT group, the CTV at 70 Gy (CTV70) was delineated as the gross target volume (GTV) plus 7mm,...