a method for the controllable synthesis of silver nanoparticles based on a complexing agent method was developed. citric acid was used as a complexing agent. the effect of ph (1.6 to 5.17) on the size and net height (as obtained from xrd analyses) of silver nanoparticles was investigated. the nanoparticles (10 to 40 nm) were characterized using xrd, tem, sem, edx, uv-vis spectroscopy and tg/dtg...

BACKGROUND In January 2014, the European Medicines Agency issued a marketing authorization for dolutegravir (DTG), a second-generation integrase strand transfer inhibitor for HIV treatment. The study aimed at determining the incremental cost-effectiveness ratio (ICER) of the use of DTG+backbone compared with raltegravir (RAL)+backbone, darunavir (DRV)+ritonavir(r)+backbone and efavirenz/tenofov...

The objective of this research was to evaluate through thermogravimetric analysis and its derivative (TG DTG), the decomposition kinetics starch present on red paddy rice submitted hydration process at temperatures 45°C, 55°C, 65° C 75°C. experimental data TG in region performed by obtaining function g (α) for kinetic mechanisms Coats – Redfern (CR) model called unidimensional contraction (R1 m...

BACKGROUND Dolutegravir (DTG; Tivicay; ViiV Healthcare, Research Triangle Park, NC) is an HIV-1-unboosted integrase inhibitor with no cytochrome P450 or uridine 5'diphosphate-glucuronosyltransferase inhibition or induction. As DTG is administered to HIV-1-infected women receiving oral contraceptives, assessing the potential for drug interactions was warranted. OBJECTIVE To determine the impac...

OBJECTIVES To evaluate the cost-effectiveness of a new generation integrase inhibitor (INI), dolutegravir (DTG), in France, in treatment-experienced (TE) and INI-naïve HIV-infected adults with at least two classes resistance compared to raltegravir (RAL), by adapting previously published Anti-Retroviral Analysis by Monte Carlo Individual Simulation (ARAMIS) model. METHODS ARAMIS is a microsim...

INTRODUCTION Dolutegravir (DTG)-based antiretroviral therapy (ART) is recommended for first-line HIV treatment in the US and Europe. Efavirenz (EFV)-based regimens remain the standard of care (SOC) in India. We examined the clinical and economic impact of DTG-based first-line ART in the setting of India's recent guidelines change to treating all patients with HIV infection regardless of CD4 cou...

Thermo-gravimetric analyses of three cellulosic substances, namely, microcrystalline and amorphous cellulose, and treated Japanese cypress (JC) sawdust were carried out in this study. The thermal degradation temperature of crystalline cellulose decreased with increasing ball-milling time, while that of amorphous cellulose barely changed. However, small differences in the derivative thermo-gravi...