Maternal or neonatal tetanus causes deaths primarily in Asia and Africa and is usually the result of poor hygiene during delivery. In 2011, three neonatal tetanus cases were investigated in Papua New Guinea, and all three cases were delivered at home by untrained assistants. The babies were normal at birth but subsequently developed spasms. A neonatal tetanus case must be viewed as a sentinel e...

INTRODUCTION Muscle rigidity and generalized spasm can cause severe pain in patients with tetanus. Administration of high dose sedative or narcotic agents can increase respiratory failure and prolong mechanical ventilation support. CASE PRESENTATION In this report, ultrasound-guided sciatic nerve block was performed in a 25-year-old patient with tetanus to progress his respiratory drive which...

He was at once put in a dark room, the ulcer was cauterized with carbolic acid and regularly treated with antiseptic dressings and the following treatment was adopted:? 23?*c? March.?Morning?6,000 international units of tetanus antitoxic serum was given intramuscularly12 a.m.?-Two c.cm. of 25 per cent magnesium sulphate solution intravenously and at 6 p.m.?0,000 international units of tetanus a...

Background. Tetanus is an acute disease caused by a neurotoxin produced by Clostridium tetani. Tetanus immunization has been available since the late 1930s but sporadic cases still occur, usually in incompletely vaccinated or unvaccinated individuals. Case Report. An elderly previously vaccinated female contracted tetanus following foot injury. Clinically she presented with meningitis causing d...

BACKGROUND Tetanus remains a major health problem in the developing world. The aim of this study was to evaluate the clinical presentation, risk factors, complications, treatment, outcome and predictors of death in patients with tetanus. METHODS Patients aged ≥ 13 years admitted to Tikur Anbessa Hospital from June 2001 to May 2009 with the diagnosis of tetanus were included in this retrospect...

n B S T R A C T The time-course of the rate of oxygen consumption ((202) has been measured in the excised frog sartorius muscle after single isometric tetani of 0.11.0 s at 20~ To measure A(2o2(t), the change in (202 from its basal level, a novel method was devised, based on the validity in this tissue of the one-dimensional diffusion equation fi)r oxygen, established in the preceding paper. Af...

BACKGROUND The group A meningococcal conjugate vaccine, PsA-TT, uses tetanus toxoid (TT) as a carrier protein (PsA-TT). TT as a carrier protein in other conjugate vaccines is known to be immunogenic and generates a robust anti-TT response. METHODS Clinical studies in Africa assessed whether PsA-TT generated tetanus serologic responses when tested in African populations (toddlers to adults). S...

BackgroundEven though there have been tremendous strides globally in reducing the burden of tetanus, neonatal deaths due to tetanus reported annually, and most occur sub-Saharan Africa which accounts for nearly half global mortality by tetanus. Immunization pregnant women or childbearing age with at least two doses toxoid is estimated reduce from 94%. Despite its importance, immunization progra...

Tetanus is an acute severe disease induced by an exotoxin, often lethal. All cases occur in untreated or inadequately vaccinated patients and mainly in elderly patients who accumulate many risk factors. The current management of wounds faced difficulties in the assessment of immunization status and wound risks status. Indeed, all injuries can potentially lead to tetanus. Minor risks and chronic...