CASE REPORT An obese 16-year-old male presented with chronic headaches and bitemporal visual field loss. Physical exam showed acanthosis nigricans and BMI of 39.8 kg/m.2 MRI of the brain revealed craniopharyngioma (Figure 1). He developed hypopituitarism after surgery, requiring Hydrocortisone, Levothyroxine, Testosterone enanthate, and desmopressin (DDAVP). Two months later, he presented with ...

The aim of this study was to determine the effects alone and combined treatment Tarantula cubensis alcoholic extract (TCAE) Methenolone Enanthate (ME) on morphometric parameters humerus femur in young rats. In study, 36 five–week–old Wistar Albino rats were used. animals divided into 4 groups; Control group (n:6, normal saline solution, 0.2 mL·rat-1, subcutaneously –SC–), TCAE (Tarantula extrac...

Adverse behavorial reactions to fluphenazine enanthate have been reported.:; "Severe depressive mood changes"6.7 and "the fulminating acute onset of schizophrenic symptomatology"ll have been attributed to fluphenazine enanthate. Allan and White9 reported a case of catatonic-like stupor and disturbed temperature regulation precipitated by a large dose (100 mg) of fluphenazine decanoate. Goldberg...

The biological effects of the testes and testosterone are known since antiquity. Aristotle knew the effects of castration and his hypothesis on fertilization is one of the first scientific encounters in reproductive biology. Over centuries, castration has been performed as punishment and to produce obedient slaves, but also to preserve the soprano voices of prepubertal boys. The Chinese imperia...

Weekly intramuscular administration of testosterone esters such as testosterone enanthate (TE) suppresses gonadotropins and spermatogenesis and has been studied as a male contraceptive. For unknown reasons, however, some men fail to achieve azoospermia with such regimens. We hypothesized that either 1) daily circulating serum fluoroimmunoreactive gonadotropins were higher or testosterone levels...

Background: Underweight chronic obstructive pulmonary disease (COPD) patients with involuntary weight loss have a poor prognosis; no effective therapy is currently available. We conducted the first clinical trial seeking to determine whether combination therapy with an appetite stimulant and an anabolic steroid would have beneficial effects on body composition for patients with COPD cachexia. M...

BACKGROUND The effects of declining androgen secretion on mood regulation and the potential psychotropic efficacy of androgen replacement in men are largely undetermined. OBJECTIVE To examine the effects on mood of the acute suppression of testosterone secretion. DESIGN A double-blind, placebo-controlled, crossover (self-as-own-control) study. SETTING An ambulatory care clinic in a resear...

BACKGROUND Development of successful anabolic strategies to reverse the loss of lean body mass is of critical importance to increase survival in men with the AIDS wasting syndrome. Hypogonadism, an acquired endocrine deficiency state characterized by loss of testosterone, occurs in more than half of all men with advanced HIV disease. It is unknown whether testosterone deficiency contributes to ...

CONTEXT Prostate safety is a primary concern when aging men receive testosterone replacement therapy (TRT), but little information is available regarding the effects of TRT on prostate tissue in men. OBJECTIVE To determine the effects of TRT on prostate tissue of aging men with low serum testosterone levels. DESIGN, SETTING, AND PARTICIPANTS Randomized, double-blind, placebo-controlled tria...