We summarize geochemical, astronomical, and theoretical constraints on the lifetime of the protoplanetary disk. Absolute Pb-Pb-isotopic dating of CAIs in CV chondrites (4567.2 ± 0.7 m.y.) and chondrules in CV (4566.7 ± 1 m.y.), CR (4564.7 ± 0.6 m.y.), and CB (4562.7 ± 0.5 m.y.) chondrites, and relative Al-Mg chronology of CAIs and chondrules in primitive chondrites, suggest that high-temperatur...

Analyse syntaxique du frann cais. Grammaire en cha^ ne. Number 2 in Etudes en linguistique frann caise et g en erale. Benjamins, Am-sterdam, 1979. Tom86] Masaru Tomita. EEcient Parsing for Natural Language. A fast algorithm for practical systems. Kluwer, Boston/Dordrecht/Lancaster, 1986. 201 p.

A prototype CAIS (cardiac arrhythmia interpretation syst/em) based on blackboard model is presented. The issue of automatic electrocardiogram analysis is addressed firstly. The idea ofbi-directional interaction is led into CAIS, which makes the system run in a kind ofway rather close to human mode of thinking. The process of PVC (premature ventricular contraction) diagnosis in CAIS is described...

Hydroxamates (R-CONHOH) have been scarcely investigated as carbonic anhydrase (CA, EC 4.2.1.1) inhibitors (CAIs). An inhibition/structural study of PhCONHOH is reported against all human isoforms. Comparing aliphatic (R = Me and CF(3)) and aromatic (R = Ph) hydroxamates as CAIs, we prove that CONHOH is a versatile zinc binding group. Depending on the nature of the R moiety, it can adopt differe...

The adult rat posterodorsal medial amygdala (MePD) is sexually dimorphic in regional volume and neuronal soma size, both of which are larger in males than in females. This sexual dimorphism is entirely dependent on adult circulating levels of testicular androgens, and both androgen and estrogen treatment can masculinize MePD structure. We examined male rats that are rendered androgen-insensitiv...

Neutrophils, the major phagocytes that form the first line of cell-mediated defense against microbial infection, are produced in the bone marrow and released into the circulation in response to granulocyte-colony stimulating factor (G-CSF). Here, we report that androgen receptor knockout (ARKO) mice are neutropenic and susceptible to acute bacterial infection, whereas castration only results in...

The spinal nucleus of the bulbocavernosus (SNB) is a sexually dimorphic motor nucleus in the rat lumbar spinal cord. The sex difference arises through the androgenic sparing of the motoneurons and their target muscles from ontogenetic cell death. Indirect evidence suggests that androgen acts on the target muscles rather than directly on SNB motoneurons to spare them from death. The testicular f...

Introduction: Chondrites are known to contain varying proportions of chondrules, matrix, refractory inclusions and metal. Although trends are known to exist among the chondrite groups (e.g. [1]), their significance has seldom been discussed and no global understanding exists to date concerning the relationship between chondrite groups. Here we show that the relative abundances of the various pe...

Introduction: It has been revealed that both of the thermal and aqueous alteration had occurred in the CV parent body [1, 2, 3]. To give a constraint to the alteration processes, the Allende meteorite can be a best example, because the following results indicate that the Allende is the strongest altered meteorite among the CV chondrites, those are: (a) homogeneity of the olivine in matrix of th...