INTRODUCTION Rituximab selectively targets CD20+ B cells and presumably protects joints in rheumatoid arthritis. Complete remissions after a single treatment with rituximab, in some cases for longer than 1 year, are observed in only the minority of patients. We reported a patient suffering from refractory rheumatoid arthritis who responded to rituximab with sustained remission. CASE REPORT A ...

Many sites are contaminated with petroleum hydrocarbons (PHCs). In some cases, these PHCs may be biorecalcitrant and therefore the soils contaminated with these PHCs are not amenable to remediation by biological treatment methods. Examples of sites containing biorecalcitrant PHCs are old flare pit sites. Flare pits are earthen pits that were once used for the storage and disposal of natural gas...

We introduce a hybrid approach to solar flare prediction, whereby a supervised regularization method is used to realize feature importance and an unsupervised clustering method is used to realize the binary flare/no-flare decision. The approach is validated against NOAA SWPC data.

Flare ups during endodontic treatment is an undesirable occurrence for both patient and clinician. Flare up phenomena is complex and not well understood which involves number of hypotheses for its etiology. Causes are numerous which include chemical, mechanical, microbial injuries to pulp and periapical tissues. This review discuss about the various etiological aspect and the management of flar...

PURPOSE To evaluate the possible inhibitory effects of Kakkon-to and Sairei-to, traditional Sino-Japanese herbal medicines, on experimental aqueous flare elevation in pigmented rabbits. METHODS Anterior uveitis was induced either by an application of prostaglandin E2 (PGE2), 10 microg/mL, to the cornea, or an intravenous injection of lipopolysaccharides (LPS), 0.5 microg/kg, in an ear vein. D...

The statistical examination of solar flares is crucial to revealing their global characteristics and behaviour. Such examinations can tackle large-scale science questions or give context to detailed single-event studies. However, they are often performed using standard but basic flare detection algorithms relying on arbitrary thresholds. This arbitrariness may lead to important scientific concl...

OBJECTIVE To describe probabilities and characteristics of disease flares in children with juvenile idiopathic arthritis (JIA) and to identify clinical features associated with an increased risk of flare. METHODS We studied children in the Research in Arthritis in Canadian Children emphasizing Outcomes (ReACCh-Out) prospective inception cohort. A flare was defined as a recurrence of disease m...

A time-dependent search for neutrino flares from pre-defined directions in the whole sky is presented. The analysis uses a time clustering algorithm combined with an unbinned likelihood method. This algorithm provides a search for significant neutrino flares over time-scales that are not fixed a-priori and that are not triggered by multiwavelength observations. The event selection is optimized ...

We present X-ray observations of the BL Lacertae object Mrk 501 that were taken with the Rossi X-Ray Timing Explorer in 1998 May as part of a multiwavelength campaign. The X-ray light curve shows a very rapid flare in which the 2-10 keV flux increased by approximately 60% in less than 200 s. This rapid rise is followed by a drop-off in the 2-10 keV flux of approximately 40% in less than 600 s. ...