Abstract Purpose Molecular imaging with 99m Tc-methoxy-isobutyl-isonitrile ( Tc-MIBI, MIBI) has been used in the assessment of thyroid nodules (TNs) for more than two decades. Many studies showed that MIBI is a suitable tool to rule-out malignancy when negative. However, relatively low specificity and accuracy have described, thus, limiting its acceptance clinical practice. Additionally, differ...

Technetium-99 is one of the most important isotopes likely to be disposed of in the proposed UK Geological Disposal Facility (GDF) for higher-activity radioactive wastes. This is due to its long half-life, high fission yield, and its ability to migrate through the geosphere when in its oxidised, pertechnetate form. However, much of the technetium in the GDF is likely to be in the lower oxidatio...

Myocardial perfusion scintigraphy (MPS) is the only widely available method of direct assessment of myocardial perfusion. It involves intravenous injection of small amounts of a radioactive tracer at peak stress, followed by imaging of the heart with a gamma camera. There are three commercially available tracers: thallium-201 and two technetium-labelled tracers, sestamibi and tetrofosmin. All t...

BACKGROUND Technetium-99m sestamibi scintigraphy has become one of the most popular techniques for localization of the parathyroid gland after failure of primary neck exploration. OBJECTIVE To examine the efficacy of sestamibi with the hand-held gamma ray detecting probe for the identification of parathyroid adenomas during revision parathyroidectomy. METHODS We reviewed six cases of probe-...

Introduction: 99m Technetium -Mebrofinate SPECT-CT scan is a pre-operative investigation useful in assessing the global, lobar and dynamic liver function. The study aimed at discordance function (scintigraphy) within given volume of remnant to assess if variation related primary indication for resection. Methods: All patients who underwent Tc-Mebrofenin unit since 2018 were included. Data proce...

We present a 77-year woman with a size of 9.5x9x7cm giant ancient schwannoma located in the lower arm. Increased activity accumulation in the tumor was seen on the Tc-99m-methylene diphosphonate bone scintigraphy. After excision of the tumor, Pathologic diagnosis could be illustrated as an ancient schwannoma. Previous studies reported that Schwannoma could be demonstrated with increased Tc-99m-...

Introduction: This study was done to determine the site of obstruction in lacrimal drainage system in Asian patients suffering from epiphora and to determine the transit time taken for the tracer material to reach the lacrimal sac and the nasal cavity. Methods:Dacryoscintigraphy was performed using radionuclide technetium-99m pertechnetate (99m...

Technetium-99 (Tc) and iodine-129 (I) are two long-lived fission products of high volatility, which makes their study in glass structure challenging. Both technetium and iodine have broad ranging multivalent chemistry and complex reactivity dependent on redox conditions; technetium and iodine redox may vary from Tc to Tc and from I to I. Relatively few studies have been done on their speciation...

To the Editor, We report a 52-year-old male patient with bone marrow and skeletal system involvement of sarcoidosis. In sarcoidosis, while bone involvement occurs at a rate of 10%-15%, iliac bone and bone marrow involvement is less common [1,2]. A 52-year-old male patient was admitted to our clinic with increased lower back pain with activity for the last 2 months. The patient occasionally coug...