Dry eye disease (DED) is one of the most common conditions encountered by ophthalmologists in their practice. Currently, experts consider meibomian gland dysfunction to be leading cause dry syndrome. This condition characterized obstruction discharge ducts and/or changes glandular secretion, which leads disturbance tear film stability and provokes inflammatory process ocular surface. The purpos...

OBJECTIVE: The purpose of this study was to ascertain the extent which ocular surface women with polycystic ovary syndrome is impacted. STUDY DESIGN: Included in case-control were 23 eyes patients (Group I) and 10 healthy subjects II). Polycystic diagnosed when two following conditions met: oligo- or anovulation, clinical and/or biochemical signs hyperandrogenism, ultrasonographic documentation...

Ocular manifestations in patients with psoriasis vulgaris have been investigated in only a small number of studies. Our purpose was to identify tear film function and ocular pathologies associated with psoriasis vulgaris in patients who had received neither oral retinoids nor phototherapy. We examined 62 eyes of 31 patients with psoriasis and 60 eyes of 30 age-and-sex matched healthy volunteers...

PURPOSE Evaporation of the tear film is heavily discussed as one core reason for dry eye disease (DED). Subsequently, new artificial tear products are developed that specifically target this pathomechanism. Perfluorohexyloctane (F6H8, NovaTears(®)) from the family of semifluorinated alkanes is a novel substance that has been approved as a medical device, as a nonblurring wetting agent for the o...

  Tears of the subscapularis tendon have been significantly recognized as a source of shoulder pain and dysfunction in the past decade, thanks to arthroscopic evaluation of the shoulder and biomechanical and anatomical studies of the tendon. Current classification of subscapularis tendon tear is based on insertion site of the tendon. Recently, a classification for non-insertional types of subsc...

Purpose The superoxide dismutase-1 knockout (Sod1-/-) mouse is an age-related dry eye mouse model. We evaluated the role of 2% rebamipide ophthalmic solution on the conjunctiva and ocular surface alterations in Sod1-/- mice. Methods Rebamipide eye drops (2%) were instilled in six 50-week-old male Sod1-/- mice and six C57BL/6 strain wild-type (WT) male mice four times a day for 2 weeks. Aqueou...

PURPOSE To assess the clinical efficacy of a newly developed disposable eyelid-warming device (Eye Warmer) for the treatment of meibomian gland dysfunction (MGD). METHODS The Eye Warmer was applied for 5 minutes to 44 eyes of 22 patients who exhibited decreased tear break-up time (BUT) and dry-eye symptoms. Its efficacy was assessed on the basis of BUT and dry-eye symptoms in the short-term s...

http://www.avehjournal.org doi:10.4102/aveh.v74i1.12 The meibomian glands of the upper and lower eyelids play a valuable role in secreting the lipid layer of the tear film. Disturbances in meibomian gland function may result in altered secretion and variations in tear composition which may lead to meibomian gland dysfunction and evaporative dry eye, leading to ocular discomfort. To diagnose and...