نتایج جستجو برای: tam selections
تعداد نتایج: 12366 فیلتر نتایج به سال:
Downregulation of Choline Kinase-Alpha Enhances Autophagy in Tamoxifen-Resistant Breast Cancer Cells
Choline kinase-α (Chk-α) and autophagy have gained much attention, as they relate to the drug-resistance of breast cancer. Here, we explored the potential connection between Chk-α and autophagy in the mechanisms driving to tamoxifen (TAM) resistance, in estrogen receptor positive (ER+) breast cancer cells (BCCs). Human BCC lines (MCF-7 and TAM-resistant MCF-7 (MCF-7/TAM) cells) were used. Chk-α...
BACKGROUND Monocyte recruited into the tumor and maturation to tumor-associated macrophage (TAM). Interleukin-10(IL-10) is a potent immunosuppressive cytokine, which can be secreted from both primary tumor and stromal cells. However, there are controversies regarding its role in the progression of cancer. So it is important to isolate TAM from tumor cells to study the role of IL-10 in the progr...
Tumor-associated macrophages (TAMs), the most abundant immunosuppressive cells in the tumor microenvironment, originate from blood monocytes and exhibit an IL-10(high)IL-12(low) M2 profile. The factors involved in TAM generation remain unidentified. We identify here leukemia inhibitory factor (LIF) and IL-6 as tumor microenvironmental factors that can promote TAM generation. Ovarian cancer asci...
The effect of tamoxifen (TAM) on human endometrii carci noma was investigated in nude mice bearing an estrogen recep tor-positive or estrogen receptor-negative tumor. The receptornegative tumor grew rapidly, and the rates of tumor growth of 17/3-estradiol or TAM-treated animals were identical to the rate of controls. The estradici receptor and progesterone receptor (PR) concentrations in the tu...
Glioblastoma is one of the most common brain tumors in adults with poor prognosis, aggressiveness, and treatment resistance. Vasculogenic mimicry (VM) consists of generating vascular-like channels by tumor cells, independent of endothelial angiogenesis. Studies showed in glioblastoma, the proportion of VM to all vascular channels is associated with poor prognosis and higher invasiveness levels....
The paper deals with affine selections of affine (both convex and concave) multifunctions acting between finite-dimensional real normed spaces. It is proved that each affine multifunction with compact values possesses an exhaustive family of affine selections and, consequently, can be represented by its affine selections. Moreover, a convex multifunction with compact values possesses an exhaust...
Let v be a grid path made of north and east steps. The lattice TAM(v), based on all grid paths weakly above the grid path v sharing the same endpoints as v, was introduced by Préville-Ratelle and Viennot (2014) and corresponds to the usual Tamari lattice in the case v = (NE). They showed that TAM(v) is isomorphic to the dual of TAM(←−v ), where←−v is the reverse of v with N and E exchanged. Our...
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