Abstract The receptor for activated C kinase 1 (RACK1) adaptor protein has been implicated in viral infection. However, whether RACK1 promotes vivo infection mammals remains unknown. Moreover, it elusive how is engaged antiviral innate immune signaling. In this study, we report that myeloid deficiency does not affect the development and survival of cells under resting conditions but renders mic...

Seeds are important for the preservation and reproduction of wild tulips in situ, but only a few studies have been carried out on their seed morphology germination characteristics. In this study, eight tulip species native to China were used. Their superficial ornamentation, relationship between germination, effects manipulating incubation temperature, coat, gibberellin (GA3) application studie...

The main objective of present research work is to formulate the Clopidogrel Fast Dissolving tablets. Clopidogrel, an antiplatelet drug, belongs to BCS Class-II and used to control Heart attack, Hypertension by inhibiting Platelet activation and aggregation .The Fast Dissolving tablets of Clopidogrel were prepared employing different concentrations of Crospovidone and Croscarmellose sodium in di...

BACKGROUND Ultrasound measurement of gastric emptying has potential advantages over scintigraphy, but there is little information about its accuracy. AIMS The relation between ultrasonographic measurements of antral area and (a) scintigraphic measurements of gastric emptying and intragastric distribution of liquids (b) postprandial satiation, were evaluated. SUBJECTS Seven normal volunteers...

Ectopic expression of decorin in a wide variety of transformed cells results in growth arrest and the inability to generate tumors in nude mice. This process is caused by a decorin-mediated activation of the epidermal growth factor receptor, which leads to a sustained induction of endogenous p21(WAF1/CIP1) (the cyclin-dependent kinase inhibitor p21) and growth arrest. However, mice harboring a ...

Thermotoga maritima is the most thermophilic eubacterium currently known and grows up to 90 degrees C by a fermentative metabolism in which H2, CO2, and organic acids are end products. It was shown that the production of H2 is catalyzed by a single hydrogenase located in the cytoplasm. The addition of tungsten to the growth medium was found to increase both the cellular concentration of the hyd...

BACKGROUND Octreotide is used in many centres to prevent complications after pancreatic surgery. Delayed gastric emptying is a another complication occurring in around 30% of patients after pancreatoduodenectomy (PD) and causes prolonged hospital stay. The influence of octreotide on this complication is doubtful. AIMS To assess the effect of octreotide, at the clinical dosage used after pancr...

National and international regulations require that chemicals must be properly classified, labeled, packaged, and transported based on their ability to damage or destroy tissue, e.g., skin. Traditionally, skin corrosion assessments were based on tests involving topical application of test substances to the skin of rabbits. In the present work, an in vitro skin corrosion test based on the use of...

Rubart, Michael, Exing Wang, Kenneth W. Dunn, and Loren J. Field. Two-photon molecular excitation imaging of Ca2 transients in Langendorff-perfused mouse hearts. Am J Physiol Cell Physiol 284: C1654–C1668, 2003. First published February 12, 2003; 10.1152/ajpcell.00469. 2002.—The ability to image calcium signals at subcellular levels within the intact depolarizing heart could provide valuable in...

OBJECTIVES Given reports on the increased prevalence of thromboembolic incidents in patients with eosinophilic granulomatosis with polyangiitis (EGPA; Churg-Strauss syndrome), we investigated whether fibrin clot properties are unfavorably altered in EGPA. METHODS Ex vivo plasma fibrin clot characteristics, including clot permeability, turbidimetry and efficiency of fibrinolysis using two assa...