Constriction of the fetal ductus arteriosus (DA) has disparate effects on mean and phasic hemodynamics, as mean DA blood flow is preserved until constriction is severe, but DA systolic and diastolic blood velocities change with only mild constriction. To determine the basis of this disparity and its physiological significance, seven anesthetized late-gestation fetal sheep were instrumented with...

A case of pulmonary stenosis due to extrinsic compression of the pulmonary artery and right ventricular infundibulum is reported. It is believed that this is the first such case recorded in the English literature where the cause of the compression was a bronchiogenic cyst. Pulmonary stenosis due to compression of the right ventricular outflow tract by an extrinsic mass is an uncommon but well-d...

We investigated the determinants of ventricular early diastolic lengthening and mechanics of suction using a mathematical model of the left ventricle (LV). The model was based on a force balance between the force represented by LV pressure (LVP) and active and passive myocardial forces. The predicted lengthening velocity (e') from the model agreed well with measurements from 10 dogs during 5 di...

UNLABELLED A 2-year-old boy found in cardiac arrest secondary to drowning received standard CPR for 35 minutes and was transported to a tertiary hospital for rewarming from hypothermia. Chest compressions in hospital were started using two-thumb encircling hands technique. Subsequently two-thumbs direct sternal compression technique and after sternal force/depth sensor placement, chest compress...

OBJECTIVES The objective was to determine the effect of myofascial techniques on the modulation of physiologic and psychologic variables. DESIGN Forty-one (41) healthy male volunteers were randomly assigned to an experimental or control group. INTERVENTIONS The experimental group underwent 3 manual therapy modalities: suboccipital muscle technique, compression of fourth intracranial ventric...

AIM To study the effect of positional change on inferior vena cava (IVC) diameter. The influence of positional change on IVC size is not well studied. Although the American Society of Echocardiography guidelines for chamber quantification recommend imaging the IVC in the left lateral position, many labs routinely image the IVC from the supine position. METHODS AND RESULTS Forty-three patients...

BACKGROUND Spinal anesthesia is a standard technique for cesarean section but can cause hypotension which may be related to venous pooling secondary to progesterone-induced decreases in vascular tone. This study investigated the use of a sequential compression mechanical pump with thigh-high sleeves with compression cycles timed to venous refilling. We hypothesized that this would recruit poole...

Background. This study investigated the effects of impairment to placental flow on flow patterns through the aortic isthmus because in the fetus, this vascular segment is the link between the parallel vascular systems perfused by the left and right ventricles. Methods and Results. A progressive increase in resistance to blood flow through the placenta was created in seven exteriorized fetal lam...