An adolescent girl, a known case of spina bifida with systemic lupus, presented with bluish discolouration of three toes of the right foot. She had thrombosis of bilateral popliteal arteries. She underwent percutaneous transluminal angioplasty (PTA) of both legs and Chopart amputation of the right foot. Systemic lupus erythematosus (SLE) occurring in a patient with spina bifida has not been pre...

Rarely, systemic lupus erythematosus (SLE) presents with bullous lesions due to severe edema and hydropic degeneration of the basal layer, or as a subepidermal blistering disease. Here, we describe two Mexican teenagers, one with SLE with blisters and another with bullous SLE. We also discuss the mechanisms and clinical implications of lesion formation in patients with SLE and bullae.

Background: We have been determined that for patients with systemic lupus erythematosus (SLE), after becoming infected with tuberculosis, the damages in their hematologic and complement systems were alleviated to a certain extent, this was an interesting phenomenon. So we hypothesized that tuberculosis infection could be useful for treating the SLE activity. Methods: In order to verify the abov...

PURPOSE OF REVIEW Systemic lupus erythematosus (SLE) is the prototypic autoimmune condition, often affecting multiple organ systems, including the skin. Cutaneous lupus erythematosus (CLE) is distinct from SLE and may be skin limited or associated with systemic disease. Histopathologically, the hallmark of lupus-specific manifestations of SLE and CLE is an interface dermatitis. The cause of SLE...

conclusions mothers with sle should be screened and closely followed up during pregnancy for the development of fetal atrioventricular (av) block. case presentation a term infant with fetal bradycardia, detected at the 23rd gestational age, was diagnosed with chb due to nls and was successfully treated with a permanent epicardial pacemaker. the patient was reported here due to rarity of the pro...

Systemic lupus erythematosus (SLE) is a chronic, autoimmune disorder involving multiple organ systems with variability in its clinical features and complexity of disease course. Ocular manifestations occur one-third SLE patients. Vision-threatening retinal vasculitis may be the initial eye presentation such cases. We herein present case teenage girl who exhibits signs symptoms after diagnosis S...

We describe a female patient with systemic lupus erythematosus (SLE) also diagnosed with Fabry's disease and anti-phospholipid antibody syndrome (APS). SLE and Fabry's disease are both systemic diseases with variable clinical presentations. Recent studies have shown a relatively high incidence of late onset Fabry's disease in female heterozygous individuals, suggesting that this condition could...

R enal involvement is frequent in patients with systemic lupus erythematosus (SLE) and may strongly influence their expectancy and quality of life. Until recently, the treatment of lupus nephritis mainly rested on three drugs: corticosteroids, cyclophosphamide, and azathioprine. However, newer agents have been introduced in the last few years. In this paper, the available treatments for lupus n...

background: antiphospholipid antibody syndrome (aps) can either occur as a primary syndrome or associated with other autoimmune diseases such as systemic lupus erythematosus (sle). anticardiolipin antibody (acl) of igg and/or igm isotype in blood, measured by a standardized elisa is the most acceptable laboratory criteria. aps igg isotype, particularly igg2 subclass is more strongly associated ...

= Abstract =Pulmonary hemorrhage is a rare and often fatal manifestation of systemic lupus erythematosus (SLE) and enters the differential diagnosis of diffuse lung disease in patients with SLE. We have recently seen massive pulmonary hemorrhage in a 24 year old SLE patient with diffuse proliferative lupus nephritis. Pulmonary hemorrhage was diagnosed by the clinical triad of hemoptysis, anemia...