background and objectives: urinary tract infection (uti) is one of the most common infections in human, and uropathogenic escherichia coli (upec) strains are the most common cause of uti. these strains colonize in bladder and cause cystitis, which could cause pyelonephritis by movement to the kidneys. since fimh protein has a very important role in colonization of upec strains and causing infec...

pigment epithelium-derived factor (pedf) is a glycoprotein that belongs to the family of non-inhibitory serpins. the broad spectrum of pedf biological activity is evident when considering its effects in promoting cell survival and proliferation, as well as its antiangiogenic, antitumor, and anti-metastatic properties. although the structural domains of the pedf gene that mediate such diverse ef...