Biomedical applications of carbon nanotubes (CNTs) often involve improving their hydrophilicity and dispersion in biological media by modifying them through noncovalent or covalent functionalization. However, the potential adverse effects of surface-functionalized CNTs have not been well characterized. In this study, we functionalized multi-walled CNTs (MWCNTs) via carboxylation, to produce MWC...

Here we present results that investigate the origins of signals observed in tip-enhanced Raman (TERS) measurements of functionalized nanoparticles. Surface enhanced Raman scattering (SERS) is known to give the largest enhancements in gap junctions. Similarly, gap-mode TERS also produces significant enhancements. The methodology developed here provides gap-mode like enhancements in TERS measurem...

There is an increasing interest in circulating microRNAs (miRNAs) as potential minimally invasive diagnostic biomarkers in oncology. Considerable efforts are being made in the development of lab-on-a-chip devices for biomedical applications to purify and detect miRNAs from biological fluids. Here, we report the development of an innovative polydimethylsiloxane (PDMS)-based parallel device whose...

A novel optical biosensor based on long-range surface plasmon-polariton (LRSPP) waveguides is demonstrated for the detection of leukemia markers in patient serum using a functionalization strategy based on Protein G. The sensor consists of thin straight Au waveguides (5 μm × 35 nm × 3.2 mm) embedded in fluoropolymer CYTOP™ with a fluidic channel etched into the top cladding. B-cell leukemia is ...

Nanocomposite cation exchange membranes (CEMs) were prepared by adding various amounts of functionalized silica-coated magnetite nanoparticles to the sulfonated polyethersulfone (sPES) polymeric matrix. The particles were synthesized first by the co-precipitation method (M0). Different surface modifications were then carried out on them by grafting three functional groups of mercaptopropyl, pro...

SBA-15 was prepared and then functionalized with N-methyl-N’-propyltrimethoxysilyl imidazolium chloride as ionic liquid moiety. The ionic liquid functionalized SBA-15 (SBA-IL) was characterized by different analytical techniques including FT-IR, N2 adsorption-desorption, TGA and SEM image. According to the obtained results it was found that the organic groups were g...

In recent years much attention has been paid to the synthesis of metal and metal oxide nanoparticles with tailored size and morphology, and to appropriate functionalization in their periphery [1]. In addition to several types of polymers, long-chain organic molecules play an important role as ligands for nanoparticles to prevent their agglomeration and to provide the necessary functionalization...