نتایج جستجو برای: suppressive therapy

تعداد نتایج: 665551  

2016
Sara C. Keller Sara E. Cosgrove Yvonne Higgins Damani A. Piggott Greg Osgood Paul G. Auwaerter

Background.  The use of suppressive antibiotics in treatment of orthopedic hardware infections (OHIs), including spinal hardware infections, prosthetic joint infections, and infections of internal fixation devices, is controversial. Methods.  Over a 4-year period at 2 academic medical centers, patients with OHI who were treated with debridement and retention of hardware components, with single-...

Journal: :Current pharmacogenomics and personalized medicine 2011
Shyam A Patel Pranela Rameshwar

Bone marrow transplantation is a form of cell therapy that has been in practice for decades for the treatment of hematological disorders and solid tumors. Immunosuppressive therapy has been a mainstay for treatment, but the severity of the adverse effects has made it an undesirable choice. Mesenchymal stem cells (MSCs), which reside in the vascular regions of the bone marrow, have been shown to...

Journal: :BMC Infectious Diseases 2007
José-Manuel Vagace Cesar Sanz-Rodriguez Maria-Soledad Casado Nieves Alonso Manuel Garcia-Dominguez Francisco Garcia de la Llana Luis Zarallo Miguel Fajardo Roberto Bajo

BACKGROUND Fusarium spp. is being isolated with increasing frequency as a pathogen in oncohematologic patients. Caspofungin and amphotericin B have been reported to have synergistic activity against Fusarium spp. CASE PRESENTATION We herein report a case of disseminated fusariosis diagnosed by chest CT scan and positive blood cultures to Fusarium spp. Because the patient's clinical condition ...

Journal: :Biological & pharmaceutical bulletin 2014
Kazuaki Matsumoto Naoko Kanazawa Akari Shigemi Kazuro Ikawa Norifumi Morikawa Toyoyasu Koriyama Michiyo Orita Hideki Kawamura Koichi Tokuda Junichiro Nishi Yasuo Takeda

The antimicrobial agents vancomycin and metronidazole have been used to treat Clostridium difficile infections (CDIs). However, it remains unclear why patients are at risk of treatment failure and recurrence. Therefore, this study retrospectively examined 98 patients with CDIs who were diagnosed based on the detection of toxin-positive C. difficile to determine the risk factors affecting drug t...

2016
Philip J. Norris Jinbing Zhang Andrew Worlock Sangeetha V. Nair Kathryn Anastos Howard L. Minkoff Maria C. Villacres Mary Young Ruth M. Greenblatt Seema Desai Alan L. Landay Stephen J. Gange C. Thomas Nugent Elizabeth T. Golub Sheila M. Keating Kathryn Anastos Howard Minkoff Deborah Gustafson Mardge Cohen Audrey French Mary Young Ruth Greenblatt Bradley Aouizerat Phyllis Tien Stephen Gange Elizabeth Golub Joel Milam

Background.  Subjects on suppressive combination antiretroviral therapy (cART) who do not achieve robust reconstitution of CD4(+) T cells face higher risk of complications and death. We studied participants in the Women's Interagency HIV Study with good (immunological responder [IR]) or poor (immunological nonresponder [INR]) CD4(+) T-cell recovery after suppressive cART (n = 50 per group) to d...

آیت اله بیاتیان, , ابوالحسن حلوانی, , محمد باقر اولیا, ,

Background: Wagener's granulomatosis (WG) is a systemic necrotizing vasculitis characterized by upper and lower respiratory tract involvement and glomerulonephritis in most instances. Case Report: We report a 36 years old man with DAH secondary to WG, as the presenting feature. He successfully treated with standard immune suppressive agents including pulse methylprednisolone and cyclophospha-m...

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