Intense exercise may cause heart remodeling to compensate increases in blood pressure or volume by increasing muscle mass. Cardiac changes do not involve only the left ventricle, but all heart chambers. Physiological cardiac modeling in athletes is associated with normal or enhanced cardiac function, but recent studies have documented decrements in left ventricular function during intense exerc...

Computerized techniques were employed to generate alternating anodal and cathodal or sequential anodal strength-interval curves during and following 15-minute coronary artery ligations in 14 anesthetized dogs. The right atrium was paced at 2.5 Hz, and unipolar ventricular strength-interval curves with simultaneous conduction times were recorded every 45-120 seconds during ischemia and reperfusi...

Disturbances in the propagation of the heart beat between the auricle and the two ventricles are of frequent occurrence and well known under the terms A-V dissociation or heart block. The term sinoauricular block is the standard name for an apparent block between the sinus node and the auricle, a hypothetical incident to explain transient auricular standstill for a period of time that is a mult...

OBJECTIVE To study how tolerance to GAD65 affects the development of autoimmunity to other beta-cell autoantigens (beta-CAAs) in GAD65-transgenic (GAD-tg) NOD mice. RESEARCH DESIGN AND METHODS We used ELISPOT to characterize the frequency and functional phenotype of T-cell responses to GAD65 and other beta-CAAs at different ages in GAD-tg mice and their NOD mouse littermates. RESULTS In you...

PURPOSE To provide an up to 14-year overview of the early ocular phenotype in siblings with a homozygous p.G461R mutation in the KCNV2 gene. METHODS Two brothers and their sister were followed-up clinically from ages 5 years, 4 years, and 2 months, respectively, including complete ophthalmological examinations. Goldmann visual fields, two-color-threshold (2CT) perimetry, color vision testing,...

Post-collisional potassic-ultrapotassic volcanic rocks are widely developed in the Lhasa block, Qinghai-Tibet region. In this paper, it was observed for first time that dilute alkali elements–Li, Rb, and Cs–exhibit supernormal enrichment research data of numerous block. At same time, there few studies on genesis enrichment. Currently, 568 sets published rock 8 measured block sorted detail, elem...