Acyl-CoA:1,2-diacylglycerol O-acyltransferase (EC 2.3.1.20) of rat liver microsomes could be inactivated in vitro by incubation with ATP, Mg2e , and a 105,000 x g rat liver supernatant. Of the nucleotides tested, ATP was the most effective in inactivating diacylglycerol acyltransferase. The rate of this inactivation was not influenced by the addition of cAMP. Treatment of rat liver microsomes w...
