The recent increase in some parts of London of syphilis acquired homosexually (Lancet, 1964; Brit. med. J7., 1967) has indicated that a drug of nontreponemicidal properties is to be preferred in the treatment of gonococcal proctitis in homosexual men. Septrin was considered as a potentially useful remedy in these circumstances. Though taken orally and so subject to error or misuse, it needs be ...

During the past few years a number of reports have indicated the therapeutic effectiveness of the new synthetic chemotherapeutic agent trimethoprim (2,4-diamino-5-(3,4,5-trimethoxybenzyl) pyrimidine) used in combination with sulphamethoxazole in a wide range of bacterial infections (Noall, Sewards, and Waterworth, i962; Schneider et al., i965; Akinkugbe et al., I968; Hughes, I969). Staphylococc...

INTRODUCTION We describe a case illustrating a rare but increasingly recognised association of chronic actinic dermatitis (CAD) with human immunodeficiency virus (HIV) infection. CLINICAL PICTURE A 40-year-old Chinese man of skin type III presented with a photodistributed rash of 3 years' duration. Histology, phototesting and subsequent clinical course were consistent with CAD. HIV serology w...

People with the variants of glucose-6-phosphate dehydrogenase (GPD) deficiency common in the southern Chinese (Canton, B(-)Chinese, and Hong Kong-Pokfulam) have a moderate shortening of red-cell survival but no anaemia when they are in the steady state. With a cross-transfusion technique, primaquine, nitrofurantoin, and large doses of aspirin were found to aggravate the haemolysis while sulpham...