OBJECTIVE To test the validity of the reported high incidence (50%) of malignancy in neoplasms of the submandibular salivary gland, and to compare it with that of the parotid gland. METHODS This is a retrospective analysis of major salivary gland neoplasms in 127 patients who were treated between August 1988 and December 2004 (15 1/2 years) at Kalafong Hospital, Pretoria. RESULTS All but 1 ...

BACKGROUND Xerostomia is a devastating complication of radiation therapy. Previous research has demonstrated that submandibular glands may be removed from the neck and transplanted using microvascular techniques, with good gland survival. However, microvascular transplantation and replantation has never been attempted on a composite tissue such as a salivary gland. OBJECTIVE To evaluate the a...

Mucoepidermoid carcinoma (MEC) is a malignant neoplasms of the salivary glands which is rarely found in childhood. Its incidence rate has been reported to be 0.44 per 100,000.1 Most of them arise from the parotid gland (64 – 80%) while other locations that are less frequent include submandibular gland, sublingual gland, minor salivary glands and lacrimal gland.2 Submandibular gland cancer is ex...

Many conditions affect the salivary glands. Acute sialadenitis is infectious or inflammatory disorders of the salivary glands. The exact frequency of submandibular sialadenitis is unclear. The acute conditions more typically involve the parotid and submandibular glands. During an acute inflammatory process, there is swelling of the affected gland, overlying pain, gland tenderness, fever, and on...

Chronic sclerosing sialadenitis (CSS) (Kuttner's tumor) is a benign fibroinflammatory condition most commonly affecting the submandibular gland. It presents as hard mass that mimics salivary gland neoplasms. We report an unusual presentation of Kuttner's tumor parotid in order to raise awareness this rare and underreported entity.

Bilateral duplication of submandibular ducts ending in a ranula was revealed by sialography and confirmed by T2weighted SSh sequence using magnetic resonance cholangiopancreatography (MRCP) parameters. A literature search revealed 2 previous reports of submandibular duct duplication, but a ranula associated with submandibular duct duplication has not been previously reported. A review of congen...

Autologous submandibular gland transplantation is an effective treatment for severe dry eye syndrome. However, the protein secretion in transplanted gland is altered by a mechanism that remains to be elucidated. In the present study, we found that β1-adrenoceptor (β1-AR) and β2-AR expression and the phosphorylation of the downstream molecule protein kinase A (PKA) were elevated in transplanted ...

To cite: Kumar S, Hasan R, Paulraj SK, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2015210969 DESCRIPTION A 75-year-old woman presented with a mildly painful mass over her right lower jaw for 3 years. The mass presented as a small nodule and progressively increased to the present size. Additional symptoms included dull aching pain in the right lower jaw...

Plexiform neurofibroma is more commonly seen in the orbit, neck, back, and inguinal region. It is extremely rare in the submandibular gland. These lesions rarely transform into malignancy but are locally infiltrative and can lead to haemorrhage. Therefore, plexiform neurofibroma should always be considered during differential diagnosis while excising a submandibular gland mass. We present here ...