Sodium and potassium-exchanging adenosine triphosphatase (Na,K-ATPase) in the kidney is associated with the subunit ( , FXYD2), a single-span membrane protein that modulates ATPase properties. Rat and human occur in two splice variants, a and b, with different N termini. Here we investigated their structural heterogeneity and functional effects on Na,K-ATPase properties. Both forms were post-tr...

The classical integer valued first-order autoregressive (INA- R(1)) model has been defined on the basis of Poisson innovations. This model has Poisson marginal distribution and is suitable for modeling equidispersed count data. In this paper, we introduce an modification of the INAR(1) model with geometric innovations (INARG(1)) for model- ing overdispersed count data. We discuss some structu...

Previous molecular dynamics simulations have shown that compression of silica glass surfaces occurs upon formation of an interface with a model crystal and that a structural change caused by this process is retained after glass and crystal are separated. The remnant structural modification caused by this stress was an increase in the concentration of siloxane bond angles less than 1508 in the n...

In this article we examine four objections to the genetic modification of human beings: the freedom argument, the giftedness argument, the authenticity argument, and the uniqueness argument. We then demonstrate that each of these arguments against genetic modification assumes a strong version of genetic determinism. Since these strong deterministic assumptions are false, the arguments against g...

the knee bracing steel frame (kbf) is a new type of energy dissipating frame which enjoys exceptional ductility and lateral stiffness. rather than the beam-column joint, one end of the diagonal brace in kbf is attached to the knee element. indeed, the knee element as a hysteretic damper is designed and detailed to behave like a structural fuse by sustaining controlled inelastic deformations as ...

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