Progesterone, an agonist for the progesterone receptor (PR), can be an efficacious andwell-tolerated treatment in endometrial cancer. The clinical use of progesterone is limited because of the lack of biomarkers that predict hormone sensitivity. Despite its efficacy in cancer therapy,mechanisms and site of action for progesterone remain unknown. Using an in vivo endometrial cancer mouse model d...

Making a decision can be especially difficult when it is based upon a large amount of information. A number of demonstrations in the literature suggest that decision making under information overload leads to suboptimal outcomes. In this article, we draw on construal level theory (Trope & Liberman, 2003) and fuzzy-trace theory (Brainerd & Reyna, 1993) to suggest that psychologically distancing ...

Participants (6- and 7-year-olds, N=130) participated in classroom activities four times. Children were interviewed about the final occurrence (target event) either 1 week or 4 weeks later, during which half of the event items were described inaccurately. Half of these suggestions were consistent with the theme of the detail across the occurrences (e.g., always sat on a kind of floor mat) or we...

Shortly after a sentence has been comprehended, information about its exact surface form (e.g., its word order) becomes less available. The present research demonstrated this phenomenon during the comprehension of nonverbal stimuli (picture stories). In Experiment 1, significantly more surface (left/right orientation) information was lost after comprehending several picture stories than just on...

People often falsely recognize items that are similar to previously encountered items. This robust memory error is referred to as gist-based false recognition. A widely held view is that this error occurs because the details fade rapidly from our memory. Contrary to this view, an initial experiment revealed that, following the same encoding conditions that produce high rates of gist-based false...

Fuzzy-trace theory has recently been used to account for various types of "false memories" (Brainerd & Reyna, 1998, this issue). Although components of fuzzy-trace theory-in particular the distinction between gist and verbatim traces-overlap with distinctions made in other theories of memory, those in fuzzy-trace theory provide an illuminating account of the conditions under which semantic asso...

UNLABELLED The prognostic value of the four most common histopathological classification systems in gastrointestinal stromal tumors (GISTs) was evaluated retrospectively. PATIENTS AND METHODS Twenty-five consecutive patients with resected GIST and a follow-up of five years or more for surviving patients were included in this analysis. All the tumors were c-KIT (CD117) positive and were additi...