Semi-synthetic must containing standard nutrients, a phenolic and aromatic fraction extracted from Albariño grapes synthetic precursors of 3-mercaptohexanol (MOH) 4-mercapto-4-pentan-2-one (MMP) were fermented with three different selected commercial S. cerevisiae yeasts. Wines subjected to anoxic aging at 50 °C for 1, 2, 5 8 weeks, their volatile composition was comprehensively determined by t...

Meteorites contain prebiotic, bio-relevant organic compounds including amino acids. Their syntheses could result from diverse sources and mechanisms provide a window on the conditions materials present in early solar system. Here we constrain alanine’s synthetic history Murchison meteorite using site-specific 13C/12C measurements, reported relative to VPDB standard. The ?13CVPDB values of ?29 ±...

Modification of the Bücherer-Strecker amino acid synthesis facilitated the production of DL-[11C]tryptophan and DL-[11C]valine for clinical trials in patients with proven or suspected pancreatic disease. Examples of rectilinear scans and tomographic images of the pancreas are presented in this initial paper. Positron computed tomography was done with the ORTEC ECAT system. Rapid localization of...

This booklet consists of the addresses delivered at the opening of the new laboratory for biochemical research at McLean Hospital. Cecil K. Drinker reviews the history of research at McLean Hospital. Jordi Foich surveys biochemical research in psychiatry with emphasis on his own contributions to the chemical constitution of the brain. The record of reasearch at the Psychiatric Service of the Ma...

Following his seminal work in 1953, Stanley Miller conducted an experiment in 1958 to study the polymerization of amino acids under simulated early Earth conditions. In the experiment, Miller sparked a gas mixture of CH4, NH3, and H2O, while intermittently adding the plausible prebiotic condensing reagent cyanamide. For unknown reasons, an analysis of the samples was not reported. We analyzed t...