Churg-Strauss syndrome is a systemic vasculitis. Its most frequent complications are heart diseases and asthma. Usually, cardiological manifestations are pericarditis, cardiac failure and myocardial infarction. Endobronchial granulomas identified by bronchoscopy are unusual. We present the case of a man with congestive cardiomyopathy and endobronchial granulomas macroscopically visible at bronc...

Several cases of eosinophilic conditions including ChurgStrauss syndrome (CSS) have recently been reported in asthmatic patients being treated with antileukotriene receptor antagonists. One patient with CSS who experienced a clinical relapse after treatment with montelukast and two asthmatic patients who developed CSS while receiving montelukast treatment are described. In one case reduction in...

Accumulating evidence shows that the central nervous system (CNS) regulates the activity of the immune system. Concerning the role of immune system in cancer, psychosocial influences on immune function provide a mechanism of association between psychosocial factors (like interpersonal aggression) and cancer prognosis. Social conflicts between males, involving high aggression stress and threat (...

Several cases of eosinophilic conditions including ChurgStrauss syndrome (CSS) have recently been reported in asthmatic patients being treated with antileukotriene receptor antagonists. One patient with CSS who experienced a clinical relapse after treatment with montelukast and two asthmatic patients who developed CSS while receiving montelukast treatment are described. In one case reduction in...

A case is presented of Churg-Strauss syndrome in a young man in whom the definitive diagnostic procedure was a full thickness sigmoidoscopic rectal biopsy, with submucosal sampling. Gastrointestinal changes in Churg-Strauss syndrome, a rare systemic illness characterised by asthma, blood and tissue eosinophilia, vasculitis, and granulomatous inflammation are common but poorly reported. The endo...

1) Mazzantini M, Fattori B, Matteucci F, et al. Neuro-laryngeal involvement in Churg-Strauss syndrome. Eur Arch Otorhinolaryngol 1998;255:302-306. 2) Hueto-Perez-de-Heredia JJ, Dominguez-del-Valle FJ, Garcia E, et al. Chronic eosinophillic pneumonia as a presenting feature of Churg-Strauss syndrome. Eur Respir J 1994;7:1006-1008. 3) Cooper BJ, Bacal E, Patterson R. Allergic angiitis and granulo...

Churg-Strauss syndrome is a rare diffuse small/medium sized vessel vasculitis that is almost invariably accompanied by severe asthma. The cause is unknown, but its characteristic histological findings and association with asthma distinguish it from other vasculitides. We report here a middle aged lady who presented with sudden onset of vasculitic skin lesions in association with long standing a...

Churg-Strauss syndrome is a rare systemic vasculitis occurring in patients with asthma and blood eosinophilia. Lungs, skin, and nervous system are the most common sites of involvement, although many other organs are affected frequently. The diagnosis often is established from clinical findings or biopsy of extrapulmonary sites, and lung biopsy is performed infrequently. The classic pathologic f...

Immunology and Center for Basic and Clinical Immunology Research (CISI), University of Federico II, Naples, Naples, Italy. Background: Churg-Strauss Syndrome (CCS) is a rare systemic necrotizing small vessel vasculitis associated with bronchial asthma, peripheral blood eosinophilia and eosinophilic lung infiltration. Skin changes compatible with vasculitis are present in about 75% of patients. ...