Screening has a central role in colorectal cancer (CRC) control. Different screening tests are effective in reducing CRC-specific mortality. Influence on cancer incidence depends on test sensitivity for pre-malignant lesions, ranging from almost no influence for guaiac-based fecal occult blood testing (gFOBT) to an estimated reduction of 66-90% for colonoscopy. Screening tests detect lesions in...

BACKGROUND The relevance of the problem of colorectal cancer (CRC) is evident because of extremely high morbidity and mortality rates, associated with this disease. CRC is mostly diagnosed only at very advanced stages. The reduction of mortality can be achieved by the popularization of screening-methods for early identification of CRC and adenomatous polyps of the colon, which are proved to be ...

Colorectal cancer causes significant morbidity and mortality and remains the second most common cause of cancer-related death in the United States. A number of screening approaches have been shown to decrease colon cancer–related mortality and are cost-effective. In this review, we discuss available screening approaches and suggest strategies to implement effective screening using the current t...

Despite the potential effectiveness of colonoscopy and fecal occult blood tests in reducing colorectal cancer mortality, more specific, noninvasive tests are desirable. In this regard, it is possible to detect specific mutations of several genes in stool samples from colorectal cancer patients. Recently, the feasibility of a multitarget assay has been explored (1,2). Because the features of the...

Condition on admission.?Temperature, 102?F.; pulse rate, 112; respirations, 26 per minute. The pulse was of fairly good volume and did not give any indication of internal haemorrhage at the time. Tongue, coated and moist. Abdomen, slightly tympanitic, resonant all over, and not rigid. No enlargement of spleen and liver. Bowels constipated for about four days after the last two hemorrhagic stool...

results oci has been reported in several high-risk groups, especially in hemodialysis patients and subjects with cryptogenic liver disease. furthermore, some studies have proposed a specific immune response for oci in comparison with chronic hepatitis c (chc). conclusions with a clinical history of approximately 11 years, occult hcv infection can be considered an occult type of chc. evidences s...

Occult gastrointestinal bleeding is defined as gastrointestinal bleeding that is not visible to the patient or physician, resulting in either a positive fecal occult blood test, or iron deficiency anemia with or without a positive fecal occult blood test. A stepwise evaluation will identify the cause of bleeding in the majority of patients. Esophagogastroduodenoscopy (EGD) and colonoscopy will ...