UNLABELLED : Human embryonic stem cells (hESCs) have an enormous potential as a source for cell replacement therapies, tissue engineering, and in vitro toxicology applications. The lack of standardized and robust bioprocesses for hESC expansion has hindered the application of hESCs and their derivatives in clinical settings. We developed a robust and well-characterized bioprocess for hESC expan...

This contribution presents program in MATLAB’s Graphical User Interface (GUI) which can be used for investigating of the static and dynamic behaviour and adaptive control of the nonlinear system represented by Continuous Stirred Tank Reactor (CSTR). Program provides computation for various values of the input variables which made this program universal for the wide range of the users without th...

An evaluation of the chromium(VI) adsorption capacity of four magnetite sorbents coated with a polymer phase containing polymethacrylic acid or polyallyl-3-methylimidazolium is presented. Factors that influence the chromium(VI) removal such as solution pH and contact time were investigated in batch experiments and in stirred tank reactor mode. Affinity and rate constants increased with the mola...

A non-linear modelling technique is presented which uses a non-parametric bilinear representation in the form of a linear and a series of bilinear impulse coefficients. The technique is applied in simulation to the identification of a non-linear continuous stirred tank reactor (CSTR) and the resulting model is shown to satisfy correlation based non-linear validity tests. It is also compared wit...

This paper deals with a catalytic continuous stirred tank reactor (CCSTR) example, mo deled as a two-input constrained nonlinear system. Based on the Lyapunov-based linearization strategy, the saturation-type parameterized control design can reduce the effect of actuator subject to amplitude and rate constraints, and the integrated two-input control framework can ensure the asymptotic output re...

In this paper, a method to build asymptotic estimators for continuous stirred tank reactor in the case of constant pressure and constant volume liquid phase is proposed. The estimator is based on the measurement of temperature and some concentrations. This method works for highly nonlinear reactions, with realistic thermodynamic properties and is based on the preservation of two fundamental con...