نتایج جستجو برای: steroidogenic acute regulatory protein

تعداد نتایج: 1805695  

2012
Kuan-Hao Tsui Jyun-Yuan Wang Leang-Shin Wu Chih-Hsien Chiu

Consumption of ponderosa pine needles causes late-term abortions in cattle and is a serious poisonous plant problem in foothill and mountain rangelands. Isocupressic acid (IA) is the component of pine needles responsible for the abortifacient effect, its abortifacient effect may be due to inhibition of steroidogenesis. To investigate the more detail molecular mechanism, we used MA-10 cell, whic...

Journal: :American journal of physiology. Endocrinology and metabolism 2012
Natasa J Stojkov Marija M Janjic Maja M Bjelic Aleksandar I Mihajlovic Tatjana S Kostic Silvana A Andric

This study was designed to evaluate the effect of acute (2 h daily) and repeated (2 h daily for 2 or 10 consecutive days) immobilization stress (IMO) on: 1) the steroidogenic machinery homeostasis; 2) cAMP signaling; and the expression of receptors for main markers of 3) adrenergic and 4) glucocorticoid signaling in Leydig cells of adult rats. The results showed that acute IMO inhibited steroid...

2011
Ana Fernanda Castillo Jinjiang Fan Vassilios Papadopoulos Ernesto J. Podestá

Cholesterol transport is essential for many physiological processes, including steroidogenesis. In steroidogenic cells hormone-induced cholesterol transport is controlled by a protein complex that includes steroidogenic acute regulatory protein (StAR). Star is expressed as 3.5-, 2.8-, and 1.6-kb transcripts that differ only in their 3'-untranslated regions. Because these transcripts share the s...

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