chemokines are biologically active peptides involved in the pathogenesis of various pathologies including brain malignancies. they are amongst primitive regulators of the development of immune responses against malignant glial tumors. the present study aimed to examine the expression of cc chemokines in anaplastic astrocytoma and glioblastoma multiform patients at both mrna and protein levels. ...

conclusions ma is nowadays the most accurate stereotactic anatomic guide for targeting the human na. it is a representative example of how stereotactic microanatomy could serve the development of stereotactic microneurosurgery. following the currently used trajectory through the alic, a dbs electrode placement within the na, targeting the ma, is feasible, allowing either na or alic stimulation....

Background Brain abscess is one of the most serious complications of head infections, with significant case-fatality rates. Great progress was made after introduction of antimicrobial therapy with improved microbiologic culture techniques, particularly for anaerobes, and stereotactic brain biopsy and aspiration techniques. The incidence of neurological sequelae in patients who survive a brain a...

Materials and methods: The charts of 29 patients with low grade gliomas were collected. Only in 19 cases of them an NMR-spectroscopic examination was performed. Due to choline, N-acetylaspartate (NAA) and lipid content the gliomas were classified into astrocytoma WHO II or III or in low or high grade gliomas. After stereotactic biopsy or neurosurgical removal histopathological examination was p...

OBJECTIVE The aim of the current prospective study was to analyse the validity of MRI based diagnosis of brainstem gliomas which was verified by stereotactic biopsy and follow-up evaluation as well as to assess prognostic factors and risk profile. METHODS Between 1998 and 2007, all consecutive adult patients with radiologically suspected brainstem glioma were included. The MRI based diagnosis...

Microcalcifications are an early mammographic sign of breast cancer and a target for stereotactic breast needle biopsy. We developed Raman spectroscopy decision algorithms to detect breast microcalcifications, based on fit coefficients (FC) derived by modeling tissue Raman spectra as a linear combination of the Raman spectra of 9 chemical and morphologic components of breast tissue. However, li...