نتایج جستجو برای: stemness

تعداد نتایج: 4177  

Journal: :Cancer Translational Medicine 2017

Journal: :Cell Cycle 2012

Journal: :Molecular Biophysics and Biochemistry 2016

Journal: :International journal of oncology 2014
Min Wang Dong Ren Wei Guo Zeyu Wang Shuai Huang Hong Du Libing Song Xinsheng Peng

Evidence in literature has demonstrated that some microRNAs (miRNAs) play a pivotal role in most solid tumor metastasis. Previous studies have showed that miR-100 is downregulated in human prostate cancer tissue compared to normal prostate and also significantly decreased in bone metastatic prostate cancer samples compared with primary prostate cancer. Argonaute 2 (AGO2) is the core effector pr...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2015
Te-Sheng Chang Yu-Chih Wu Ching-Chi Chi Wei-Chi Su Pey-Jium Chang Kam-Fai Lee Tao-Hsin Tung Jui Wang Jun-Jen Liu Shui-Yi Tung Liang-Mou Kuo Hong-Nerng Ho Thai-Yen Ling Yen-Hua Huang

PURPOSE To unravel the role of interleukin (IL)-6 and insulin-like growth factor (IGF)-I receptor (IGFIR) in expressing stemness-related properties and to evaluate the prognostic values of pluripotent transcription factor OCT4/NANOG, and IGFIR in hepatocellular carcinoma (HCC). EXPERIMENTAL DESIGN Serum levels of IL6 were detected using ELISA assays (n = 120). The effects of IL6/IGFI on stemn...

2018
S Subi S J Lee S Shiwani N K Singh

OBJECTIVE Myogenic satellite cells were isolated from semitendinosus muscle of prepubertal Korean black goat to observe the differential effect of linolenic and retinoic acid in thepresence of thiazolidinediones (TZD) and also to observe the production insulin sensitive preadipocyte. METHODS Cells were characterized for their stemness with cluster of differentiation 34 (CD34), CD13, CD106, CD...

2015
TERUYA NAGAHARA HIDENORI SHIRAHA HIROAKI SAWAHARA DAISUKE UCHIDA YASUTO TAKEUCHI MASAYA IWAMURO JUNRO KATAOKA SHIGERU HORIGUCHI TAKESHI KUWAKI HIDEKI ONISHI SHINICHIRO NAKAMURA AKINOBU TAKAKI KAZUHIRO NOUSO KAZUHIDE YAMAMOTO

Microenvironment plays an important role in epithelial-mesenchymal transition (EMT) and stemness of cells in hepatocellular carcinoma (HCC). Epithelial cell adhesion molecule (EpCAM) is known as a tumor stemness marker of HCC. To investigate the relationship between microenvironment and stemness, we performed an in vitro co-culture assay. Four HCC cell lines (HepG2, Hep3B, HuH-7 and PLC/PRF/5) ...

Journal: :cell journal 0

objective: to study the effects of different matrices and co-culture systems on cultured limbal stem cells (lscs). materials and methods: limbal explants were co-cultured with limbal fibroblasts (lf) and/or mouse embryonic fibroblasts (mef) on filter inserts coated with amniotic membrane (am), matrigel (mat) and collagen type i (col). results: this study revealed that am facilitated the cell mi...

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