dear editor multiple sclerosis (ms) is the most common inflammatory demyelinating disease of the central nervous system. ms is characterized by dissemination in time and place. dissemination can be clinically (clinically definite multiple sclerosis) or radiologically by magnetic resonance imaging (mri). correct diagnosis of ms needs dissemination both in time and in place and also exclusion of ...

The synthesis of β-thiolactone and β-lactam analogs of tetrahydrolipstatin is described from a common late-stage β-lactone derivative. These analogs, and a cis-disubstituted β-lactone analog of tetrahydrolipstatin, were screened for activity against porcine pancreatic lipase and for inhibition of cell growth of a panel of four human cancer lines.

This article examines the important role of renewable natural resources to ensure sustainable economic development CIS member states. A new stage is taking place in cooperation Commonwealth States using clean energy light adoption Priority Plan implement Concept for Cooperation Member by Renewable Energy Sources 2021-2022. In this article, special attention paid sources, as well prospects hydro...

Background: Variability in speech performance is a major concern for children with cochlear implants (CIs). Spectral resolution is an important acoustic component in speech perception. Considerable variability and limitations of spectral resolution in children with CIs may lead to individual differences in speech performance. The aim of this study was to assess the correlation between auditory ...

cross infections (cis) are considered as a major public health problem worldwide. they cause delay in recovery, increased mortality and morbidity. the purpose of this study is to report the incidence of cis in our teaching hospital during a 23-month period.in this descriptive cross-sectional study, 76766 patients from 2009 to 2011 admitted to 17 wards of imam reza hospital in mashhad were studi...

in this paper, absorption spectra of both solution and films of cyano azobenzene polymer are investigated. the analysis of overlapped absorption spectra of polymer, related to trans and cis isomers, shows that the population of cis isomers is higher than trans isomers. it means that, cyano azobenzene molecules have a folded structure in polymer, in thermal equilibrium. presence of cyano molecul...

The establishment of dorsoventral polarity in the Drosophila oocyte and future embryo is dependent on the efficient transport of K10 mRNA from nurse cells into the oocyte. To investigate the cis-requirements of K10 mRNA transport, we used a transgenic fly assay to analyze the expression patterns of a series of K10 deletion variants. Such studies identify a 44 nucleotide sequence within the K10 ...

All-trans retinoic acid (RA) is a key player in many developmental pathways. Most methods used to study its effects in development involve continuous all-trans RA activation by incubation in a solution of all-trans RA or by implanting all-trans RA-soaked beads at desired locations in the embryo. Here we show that the UV-driven photo-isomerization of 13-cis RA to the trans-isomer (and vice versa...