PURPOSE The computed tomogram angiography (CTA) 'spot sign' describes foci of intralesional enhancement associated with hematoma expansion in primary intracerebral hemorrhage patients. A consistent radiological definition is required for two proposed recombinant Factor VIIa trials planning patient dichotomization according to 'spot sign' presence or absence. We propose radiological criteria for...

MOTIVATION To study lowly expressed genes in microarray experiments, it is useful to increase the photometric gain in the scanning. However, a large gain may cause some pixels for highly expressed genes to become saturated. Spatial statistical models that model spot shapes on the pixel level may be used to infer information about the saturated pixel intensities. Other possible applications for ...

The variable (V) regions of immunoglobulin heavy and light chains undergo high rates of somatic mutation during the immune response. Although point mutations accumulate throughout the V regions and their immediate flanking sequences, analysis of large numbers of mutations that have arisen in vivo reveal that the triplet AGC appears to be most susceptible to mutation. We have stably transfected ...

Packet contention is one of the fundamental problems that must be overcome in designing packet switches. In banyan network, which has multistage interconnection structure of many small switch elements, we must be concerned with output port conflicts and internal collisions. Dilated banyan network which provides multiple path for internal link can reduce packet loss due to internal collisions in...

A laminated beam-spot camera of length 20 cm and effective cross-sectional area 2.5 cm × 3 cm was designed and constructed for the measurement of X-ray beam-spot sizes on different models of Siemens accelerators. With the accelerator gantry at 180° and camera positioned on an accessory tray holder, an XV film placed in contact with the camera at the distal end of it detected those X-rays that w...

When visual stimuli that cover the entire blind spot are presented monocularly, the color and brightness of the surrounding field are seen within the blind spot, although it receives no retinal input. Important questions about such perceptual filling-in are whether neurons in the visual system representing visual field locations within the blind spot are activated when filling-in occurs and, if...

Purpose To investigate the effect of selective retina therapy (SRT) on the release of AMD-relevant cell mediators, such as matrix metalloproteinases (MMPs), VEGF, and pigment epithelium derived factor (PEDF) using different laser spot sizes and densities. Methods Porcine RPE-choroid explants were treated with a pulsed 532 nm Nd:YAG laser using (1) large spot sizes, (2) small spot sizes with a...

B2B spot market has grown rapidly and become an effective trading channel for commodity products. Besides long-term contract procurement from conventional suppliers (forward and option), a buyer can procure or sell commodities at any time in B2B spot market to adjust her inventory level. However, spot prices are generally volatile and the market is imperfect in the sense that spot trading may b...

BACKGROUND AND PURPOSE The CT angiography (CTA) spot sign predicts hematoma expansion and poor outcome in patients with primary intracerebral hemorrhage (ICH). The biological underpinnings of the spot sign remain poorly understood; it may be that the underlying vasculopathy influences its presence. Therefore, we conducted a study to identify genetic predictors of the spot sign. METHODS In an ...

Spot market provides the ideal mechanism to leverage idle CPU resources and smooth out the computation demands. Unfortunately, few applications can take advantage of spot market because they cannot handle sudden terminations. We describe Spot Cloud MapReduce, the first MapReduce implementation that can fully take advantage of a spot market. Even if a massive number of nodes are terminated regul...