The anodic substitution reaction proceeded smoothly without affecting the oxidation of the nucleophile in a one-step electrochemical operation using acoustic emulsification.

Objective: This study aimed to develop a topical nanoemulsion using clove oil and ethanol extract of catharanthus roseus (L.) G. for antioxidant antibacterial dosage form. Methods: The was produced spontaneous emulsification method. formulation carried out tween 80 pluronic 127 as surfactants with different concentrations (0.5–2%). characterizations the formula included organoleptic test, homog...

the aim of this investigation was to design and develop nanoemulsions (nes) as novel ophthalmic delivery systems for brinzolamide (bzd). phase behavior of quaternary systems composed of triacetin and capryoltm 90 (selected oils, screened through the solubility studies), various surfactants (namely, cremophor rh 40, brij 35, labrasol and tyloxapol), transcutol p (as co-surfactant) and water a...

BACKGROUND The main treatments for cancers are still chemotherapy and radiotherapy for intermediate-stage cancer and terminal cancer. However, the therapeutic methods often result in a decreased neutrophilic granulocyte count and other side effects. In this study, in order to improve the neutrophilic granulocyte levels in the blood after radiotherapy and chemotherapy, we developed a sustained-r...

in this work, an environmentally friendly sample pre-treatment method, ultrasound assisted surfactant enhanced emulsification microextraction (uaseme) followed with spectrofluorimetry was performed for determination of oxadiazon residues in water samples. after the determination of the most suitable extraction solvent and its volume, other parameters such as type and concentration of surfactant...

in this study, simple and efficient ultrasound-assisted emulsification microextraction (usaeme) combined with gas chromatography-flame ionization detector (gc-fid) was developed for the preconcentration and determination of carbamazepine in biological samples. in this method, the fine droplets of 1-octanol were formed and dispersed in the sample with the help of ultrasonic waves, which accelera...

Background: Lower-brain glucose uptake is commonly present before the onset of cognitive deterioration associated with aging and may increase the risk of Alzheimer disease. Ketones are the brain’s main alternative energy substrate to glucose. Medium-chain triglycerides (MCTs) are rapidly b-oxidized and are ketogenic but also have gastrointestinal side effects. We assessed whether MCT emulsifica...

BACKGROUND The aim of this study was to determine the expression of apoptotic factors Bax, Bcl-2, and Caspase-3 in lens epithelial cells (LECs) from cataracts secondary to pars plana vitrectomy with silicone oil (SO) tamponade. We also investigated the impact of SO emulsification on the expression of apoptotic factors. MATERIAL/METHODS Anterior capsulotomy specimens of 20 eyes in 20 patients ...

The present study aimed to develop and optimize a nanoemulsifying preconcentrate formulation of curcumin with good emulsification ability and optimal globule size, for controlled targeting in colon. Content of formulation variables, namely, X1 (Peceol), X2 (Cremophor-EL), and X3 (Transcutol HP), were optimized by Box-Behnken design of experiments for its impact on mean globule size (Y1), emulsi...

Alginate-dextran sulfate-based particles obtained by emulsification/internal gelation technology can be considered suitable carriers for oral insulin delivery. A rational study focused on the emulsification and particle recovery steps was developed in order to reduce particles to the nanosize range while keeping insulin bioactivity. There was a decrease in size when ultrasonication was used dur...