spinal cord injury (sci) leads to a significant health problem associated with a broad range of secondary complications and disabilities. in this regard, animal models can help us to understand the pathobiology of sci and evaluate the effects of potential treatments for sci. in contusion models of sci, different devices including surgical spring-loaded clips, balloons, forceps, weights and the ...

prevalence of spinal cord injury (sci) in iran is considerable and developing a national registry is substantial. registry can be a foundation of efforts for patient care improvement, clinical research facilitation, preventative strategy formulation and policymaking for better support of patients. with respect to long-term and multiple consequents of the lesions that will have a negative impact...

the pathology of spinal cord injury (sci) comprises multiple processes characterized by extensive cell death and glial scar formation, which together limits axonal regeneration. in particular, variations in chronic demyelination of the lesion have been found to be largely independent of injury intensity, suggesting a secondary pathologic origin. this chronic demyelination results in progressive...

background and importance: disk sequestration can be defined as a herniated disk with perforation of the fibrous ring (or outermost annulus fibrosus) and posterior longitudinal ligament with migration of the disk fragment to the epidural space. even after the introduction of high-resolution magnetic resonance imaging (mri), it is still frequently misinterpreted as neoplastic masses. unfortunate...

hereby we report a patient with thalassemia major having extradural cord compression at t3-t9 levels due to a mass of extramedullary hematopoiesis (emh) tissue, whose treatment was successful with hypertransfusion therapy alone. the patient was a 23-year-old man who had not received regular blood transfusion since two years before admission. he suffered from paraparesis with a history of progre...

the quality of subarachnoid block can be improved by adding opioids to the local anesthetics. we compared the analgesic effects of different doses of intrathecal sufentanil added to lidocaine %5 for elective cesarean section. this study was a prospective, randomized, double-blind, controlled trial. 90 pregnant women with asa class i-ii, scheduled for elective cesarean section under spinal anest...

background: shivering is one of the common problems in spinal anesthesia. the objective of the present study was to evaluate the effect of intrathecal fentanyl (25 μg) on incidence and severity of intraoperative and postoperative shivering. methods: a double-blind randomized controlled study was conducted in eighty healthy women (asa physical status i) scheduled for elective cesarean section un...

how to cite this article: bani hashem a, heydarian f, gharavi m, khoshnod m. postdural puncture headache: incidence and risk factors in children followingintrathecal chemotherapy. iranian journal of child neurology 2012;6(1):19-22. objective to evaluate the incidence and risk factors of development of postdural puncture headache in children who had intrathecal chemotherapy injection. materials ...

in this study organotypic adult spinal cord slices were used to investigate whether caspases could participate in the apoptosis of motor neurons. the thoracic region of spinal cord was sliced using a tissue chopper and cultured in a medium for 6h. morphological and biochemical features of apoptosis were assessed by fluorescent staining and terminal deoxynucleotidyl nick end labeling (tunel) met...

conclusions the addition of 2.5-3 mcg sufentanil to 15 mg 0.05% bupivacaine maintained the patient’s hemodynamic stability similar to fentanyl. intrathecal sufentanil added to bupivacaine,when compared with fentanyl, may lead to prolonged duration of analgesia, facilitate the spread of the sensory block, increase mean spo2 levels, and reduce overall side effects. background the addition of intr...