results seminal plasma tac level in normospermic men was significantly higher than asthenoteratospermic men (p < 0.001) and oligasthenoteratospermic men (p < 0.001) and had posetive correlation with sperm count, motility and morphology. in contrast mda levels in normospermic men were significantly lower than in asthenoteratospermic men (p = 0.049) and oligoasthenoteratospermic men (p = 0.001) a...

We investigated whether letrozole (2.5 mg day(-1)) improves sperm count in non-obstructive azoospermia (NOA) patients. Four men were included in this study, and they had folliculo-stimulating hormone and other hormone levels within the normal range and no varicoceles or chromosomal aberrations. These four patients were administered letrozole for 3 months. Sperm count, testicular volume, gonadot...

Background and Aims: Cola acuminata pod extract (CAPE) is used in Nigerian traditional medicine to treat low sperm count in males. Hence, this study aimed to investigate the effects of CAPE on the reproductive system of male albino rats. Materials and Methods: Preliminary acute toxicity testing, phytochemical screening, proximate analysis, and determination of vitamin E concentration were perf...

OBJECTIVE To evaluate the effects of recent and long term occupational lead exposure on indicators of male reproductive health. METHODS In a cross sectional study of male employees of a lead smelter (n = 2469), blood samples were obtained from 152 workers including 119 who also provided semen samples. Semen analysis and serum concentrations of testosterone, follicle stimulating hormone, and l...

BACKGROUND A high body mass index (BMI) has been associated with reduced semen quality and male subfecundity, but no studies following obese men losing weight have yet been published. We examined semen quality and reproductive hormones among morbidly obese men and studied if weight loss improved the reproductive indicators. METHODS In this pilot cohort study, 43 men with BMI > 33 kg/m² were f...

BACKGROUND Benzo(a)pyrene (BaP) is an endocrine toxicant that is widely distributed in the environment. The adverse effects of BaP on fertility are well documented, however its effects on fertility in the subsequent generations are not known. We aimed to investigate the transgenerational effects of BaP on male fertility in mice. METHODS Six-week-old male mice (F0) were orally administered BaP...

Background: Chronic ethanol abuse causes reproductive organ failure and infertility in both humans and laboratory animals. Since sperm has a critical role in reproductive function, the objective of this unique study was to evaluate the effects of different doses of ethanol on sperm parameters, chromatin structure and apoptosis in adult mice. Materials and Methods: A total of 36 adult male mice ...

background & objectives : the purpose of this study was to compare the success rate of intracytoplasmic sperm injection cycles (icsi) between infertile war victims & other infertile couples . materials & methods :this retrospective study was done on 672 infertile couples in kossar fertility & impotence center from 2000-2002. poisson, chi-square & t–test were used to compare the icsi results in ...

background: saccharin is an artificial non-caloric sweetener that used to sweeten products such as drinks, candies, medicines, and toothpaste, but our bodies cannot metabolize it. sodium saccharin is considered as an important factor in tumor promotion in male rats but not in humans. objective: the objective of this study was to investigate the effect of saccharin consumption on sperm parameter...

The role of estrogen receptor alpha (ER alpha) and estrogen receptor beta (ER beta) gene polymorphisms on semen quality is the aim of our study. One hundred fourteen men were examined in the In Vitro Fertilization Unit of Ioannina Medical School, and it was found that 85 men had normal sperm count and 29 were oligozoospermic. The genotype analysis, on DNA extracted from spermatozoa, revealed th...