isotherms of the binding of the anthracyciine antibiotic, adriamycin (adriblastin), to dna histone complexes was studied by means of spectroscopic analysis. the results indicated that: (a) binding of adriamycin to histones reduced the interaction of histones with dna, (b) binding of the drug to dna did not change the binding affinity of histone to dna and, (c) in the explored binding range of r

PURPOSE To determine the incremental benefit of combined endorectal magnetic resonance (MR) imaging and MR spectroscopic imaging, as compared with endorectal MR imaging alone, for sextant localization of peripheral zone (PZ) prostate cancer. MATERIALS AND METHODS This prospective multicenter study, conducted by the American College of Radiology Imaging Network (ACRIN) from February 2004 to Ju...

Spectroscopic optical coherence tomography (spectroscopic OCT) is an echographic-like optical method for biomedical functional imaging. Current spectroscopic optical coherence tomography (OCT) methods rely on a posteriori numerical calculation. We present an alternative for optically accessing the spectroscopic information in OCT, that is, without postprocessing, by using a grating-based correl...

We present optical interferometric observations of two double-lined spectroscopic binaries, HD 6118 and HD 27483, taken with the Palomar Testbed Interferometer (PTI) in the K band. HD 6118 is one of the most eccentric spectroscopic binaries and HD 27483 a spectroscopic binary in the Hyades open cluster. The data collected with PTI in 2002-2003 allow us to determine astrometric orbits and when c...

We use the deepest and most complete redshift catalog currently available (the Hubble Deep Field (HDF) North supplemented by new HDF South redshift data) to minimize residuals between photometric and spectroscopic redshift estimates. The good agreement at zspec < 1.5 shows that model libraries provide a good description of the galaxy population. At zspec ≥ 2.0, the systematic shift between phot...

We have extracted 565 neutron spectroscopic factors of sd and fp shell nuclei by systematically analyzing more than 2000 measured (d, p) angular distributions. We are able to compare 125 of the extracted spectroscopic factors to values predicted by large-basis shell-model calculations and evaluate the accuracies of spectroscopic factors predicted by different shell-model interactions in these r...

Lipid is a common constituent in atherosclerotic plaques. The location and area of the lipid region is closely related to the progression of the disease. Intravascular photoacoustic (IVPA) imaging, a minimally invasive imaging modality, can spatially resolve the optical absorption property of arterial tissue. Based on the distinct optical absorption spectrum of fat in the near infrared waveleng...

Spectroscopic imaging (SI) is a method that enables the measurement of the spatial distribution of metabolite concentrations in tissue. In this paper, an overview of measurement and processing techniques for SI is given. First, the basic structure of SI pulse sequences is introduced and the concepts of k-space, point spread function and spatial resolution are described. Then, special techniques...