background: breast cancer is the most common cancer in women worldwide. recently, natural remedies such as naringenin (nar) - a kind of flavonoids which can be found in grapefruits, oranges, and tomatoes - seem to be interesting. they play a useful role in treatment and chemoprevention because of having pleiotropic molecular mechanisms of action on breast cancer cells. methods: we performed a p...

the aim of this study was to evaluate the defense cells changes of cervical mucous during follicular and luteal phases of estrus cycle in river buffalo. reproductive organs of the adult and apparently healthy female buffaloes were collected from the slaughterhouse. by visual investigation of both the ovaries for presence of corpus luteum and growing follicles, the luteal and follicular phase of...

in this present study, we examined the differentiation potential of human bone marrow derived mesenchymal stem cells (hbmscs) into hepatocytes on a three-dimentional (3d) nanofibrous scaffold formed by poly (ε-caprolactone) (pcl), collagen and polyethersulfone (pes). the nanofiber was prepared by the electrospining technique. hbmscs were isolated using combining gradient density centrifugation ...

in order to perform a histomorphometric study of blood cells in male adult ostrich, blood samples were obtained from jugular vein of 10 clinically healthy male adult ostriches (2 - 3 years old). the slides were stained with the giemsa methods and the smears were evaluated for cellular morphology, with cellular size being determined by micrometry. the findings of this study revealed that the sha...

objective(s): electrospun nanofibrous mats of poly(lactic acid) (pla) and nanohydroxyapatite (nano-ha) were prepared and proliferation and differentiation of mesenchymal stem cells on the prepared nanofibers were investigated in this study. materials and methods: pla/nano-ha nanofibers were prepared by electrospinning. the effects of process parameters, such as nano-ha concentration, distance, ...

introduction: constipation is one of the most common complaints of individuals, which may present with complication like hemorrhoid and fissure. hirschsprung is a disease presenting with chronic constipation and its diagnosis may be delayed until adulthood. it is diagnosed by biopsies from anorectal transitional zone. this study aimed to evaluate the association between hirschsprung and anorect...

a common pathological process that occurred after brain injury is gliosis. gliosis involves the activation of glial cells to proliferate and become hypertrophic to occupy the injured brain areas. in order to form a defense system against the invasion of micro-organisms and cytotoxins into surrounding tissue, glial cells including astrocytes and microglia undergo reactive response to injury. neu...

objective(s)progesterone is a steroid hormone whose biology has been greatly studied within the confines of reproductive function. in recent years, the neuroprotective effects of progesterone have attracted growing interest. glial cell line-derived neurotrophic factor (gdnf), is a neurotrophic factor which plays a crucial role in the development and maintenance of distinct sets of central and p...

objective(s): the aim of this study was to determine the important molecules involved in apoptosis induction by opium in jurkat cell line. materials and methods: jurkat cells were incubated 48 hrs with2.86×10-5 g/ml concentration of opium and apoptosis as well as expression levels of related molecules weremeasured. results: our results demonstrated that 50.3±0.2 percent of opium treated jurkat ...