نتایج جستجو برای: sonodynamic therapy

تعداد نتایج: 653817  

2012
Nagahiko Yumita Yumiko Iwase Koji Nishi Hajime Komatsu Kazuyoshi Takeda Kenji Onodera Toshio Fukai Toshihiko Ikeda Shin-ichiro Umemura Kazuho Okudaira Yasunori Momose

In this study, we investigated the induction of apoptosis by ultrasound in the presence of the novel porphyrin derivative DCPH-P-Na(I). HL-60 cells were exposed to ultrasound for up to 3 min in the presence and absence of DCPH-P-Na(I), and the induction of apoptosis was examined by analyzing cell morphology, DNA fragmentation, and caspase-3 activity. Reactive oxygen species were measured by mea...

Journal: :Bioengineering & translational medicine 2023

Melittin, the principal constituent in bee venom, is an attractive candidate for cancer therapy. However, its clinical applications are limited by hemolysis, nonspecific cytotoxicity, and rapid metabolism. Herein, a novel genetically engineered vesicular antibody-melittin (VAM) drug delivery platform was proposed validated targeted combination VAM generated from cellular plasma membrane bio-syn...

2017
Maryam Bakhshizadeh Toktam Moshirian Habibollah Esmaily Omid Rajabi Hooriyeh Nassirli Ameneh Sazgarnia

Objectives Low penetration depth of light is the main defect of photodynamic therapy (PDT), which could be improved by sonodynamic therapy (SDT). In this study, a combination of PDT and SDT known as sonophotodynamic therapy (SPDT) was investigated using two reverse arrangements in CT26 tumor model. Materials and Methods The liposomal zinc phthalocyanine was synthesized and characterized. It w...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه علوم بهزیستی و توانبخشی - دانشکده توانبخشی 1393

abstract objectives gradual increase length and complexity of utterance (gilcu) therapy method is a form of operant conditioning. this type of treatment is very precise and controlled that is done in 54 steps in 3 speech situations consisted of monologue, reading and conversation. this study aimed to examine the effects of gilcu treatment method on reduction of speech dysfluency of school-age...

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